非小细胞肺癌患者血清同型半胱氨酸、血浆D-二聚体水平的变化及其临床意义  

Levels and clinical significance of homocysteine in serum and D-dimer in plasma of patients with non-small cell lung cancer

作　　者：冯宇娇[1] 康艳[1] 裴彩丽 田学智[1] Feng Yujiao;Kang Yan;Pei Caili;Tian Xuezhi(Department of Clinical Laboratory,Shanxi Provincial Cancer Hospital,Taiyuan 030013,China)

机构地区：[1]山西省肿瘤医院检验科,太原030013

出　　处：《中国实用医刊》2020年第4期32-34,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨非小细胞肺癌(NSCLC)患者血清同型半胱氨酸、血浆D-二聚体水平的变化及其临床意义。方法抽取2016年6月至2019年7月山西省肿瘤医院收治的126例非小细胞肺癌患者作为研究组,另选取同期体检的126例健康人群作为对照组。两组均接受血清同型半胱氨酸、血浆D-二聚体检测,比较两组组间、组内(研究组治疗前、后)血清同型半胱氨酸、血浆D-二聚体的检测值。结果研究组非小细胞肺癌患者治疗前血清同型半胱氨酸、血浆D-二聚体水平高于对照组(P<0.05);研究组患者治疗结束后血清同型半胱氨酸、血浆D-二聚体水平低于治疗前(P<0.05)。结论血清同型半胱氨酸、血浆D-二聚体水平可作为诊断非小细胞肺癌患者病情及判断疗效的主要参考依据。Objective To investigate the levels and clinical significance of homocysteine in serum and D-dimer in plasma of patients with non-small cell lung cancer .Methods A total of 126 patients with non-small cell lung cancer who were admitted to Shanxi Provincial Cancer Hospital from June 2016 to July 2019 were selected as the study group, another 126 healthy people who came to hospital for physical examination during the same period were selected as the control group. The serum homocysteine and plasma D-dimer were detected in both groups, and the results were compared between the two groups and within the study group (before and after treatment).Results The serum homocysteine and plasma D-dimer levels in study group were higher than those in control group (P<0.05). In study group, the serum homocysteine and plasma D-dimer levels after treatment were lower than those before treatment (P<0.05).Conclusions Serum homocysteine and plasma D-dimer levels can be used as the main reference in the diagnosis of non-small cell lung cancer.

关 键 词：非小细胞肺癌 同型半胱氨酸 D-二聚体 

分 类 号：R734[医药卫生—肿瘤]