精神分裂症患者抗精神病药物治疗的肌红蛋白水平分析  

Analysis of myoglobin levels in patients with schizophreniaby antipsychotics

作　　者：孔国强[1] 崔德艳 陈英[1] 田玉杰 马朝阳 姜涛[1] KONG Guoqiang;CUI Deyan;CHEN Ying;TIAN Yujie;MA Chaoyang;JIANG Tao(Department of Clinical Laboratory,Beijing Anding Hospital Affiliated to Capital Medical University,Beijing 100088,China)

机构地区：[1]首都医科大学附属北京安定医院临床检验科,北京100088

出　　处：《检验医学与临床》2020年第S01期11-13,共3页Laboratory Medicine and Clinic

基　　金：北京市医院管理局重点医学专业精神分裂症专业项目(ZYLX201807)。

摘　　要：目的分析精神分裂症患者抗精神病药物治疗的肌红蛋白(Mb)水平,阐明微量Mb水平与精神分裂症患者急性期和缓解期进展的关系。方法随机工作日选取精神分裂症患者74例,分别在急性期和缓解期检测Mb水平,同时以阳性与阴性症状量表评定患者的阳性症状和阴性症状。结果住院精神分裂症患者急性期和缓解期Mb水平比较,差异有统计学意义(P<0.05),在阳性症状组比较差异也有统计学意义(P<0.05),在阴性症状组差异无统计学意义(P>0.05)。结论Mb水平可以用来评价精神分裂症患者急性症状缓解的生物学指标。Objective To analyse of myoglobin(Mb)levels in patients with schizophrenia by antipsychotics(APS),to elucidate the relationship between micro Mb level and acute and remission progression in schizophrenia.Methods A total of 74 samples from patients with schizophrenia were collected to determine Mb levels at acute phase and convalescencephase.Results The Mb levels of cases in inpatient acute phase were significantly higher than convalescence phase,the difference was statistically significant(P<0.05),the difference was statistically significant in the positive symptom group(P<0.05),the difference was not statistically significant in the negative symptom group(P>0.05).Conclusion The Mb levels could be used to evaluate the biological indicators of the recovery of the main positive symptoms in schizophrenic patients.

关 键 词：精神分裂症 抗精神病药物 肌红蛋白 

分 类 号：R74[医药卫生—神经病学与精神病学]