多项指标检测在胸腔积液与腹水性质鉴别诊断中的应用  

Application of multiple indexes in differential diagnosis of thoracic and peritoneal effusions

作　　者：刘海波 胡晓卫 卢佩 杨麦贵 梅盛林 LIU Haibo;HU Xiaowei;LU Pei;YANG Maigui;MEI Shenglin(Department of Clinical Laboratory,the Traditional Chinese Medicine Hospital of Shannxi,Xi′an,Shannxi 710003,China;Department of Clinical Laboratory,Xijing Hospital Affiliated to Air Force Military Medical University,Xi′an,Shannxi 710032,China;Xi′an Jiaotong University Stomatology Hospital,Xi′an,Shannxi 710004,China)

机构地区：[1]陕西省中医医院检验科,陕西西安710003 [2]空军军医大学西京医院检验科,陕西西安710032 [3]西安交通大学口腔医院,陕西西安710004

出　　处：《检验医学与临床》2020年第S01期79-82,共4页Laboratory Medicine and Clinic

摘　　要：目的探讨胸腔积液与腹水腺苷脱氨酶(ADA)、癌胚抗原(CEA)、总蛋白(TP)、C反应蛋白(CRP)水平和细胞学对胸腔积液与腹水性质鉴别诊断的价值。方法对273例诊断明确患者的胸腔积液与腹水进行CEA、ADA、TP、CRP和细胞学测定并进行统计学分析。结果非炎症组白细胞计数低于其他两组(P<0.05),结核组淋巴细胞所占比例高于其他两组(P<0.05),恶性组间皮细胞所占比例最高,而结核组间皮细胞所占比例最低;结核组ADA、CRP含量高于其他两组(P<0.05),恶性组CEA含量高于其他两组(P<0.05),结核组和恶性组TP含量均高于非炎症组(P<0.05)。结论胸腔积液与腹水CEA、ADA、TP、CRP水平和细胞学检测能够作为胸腔积液与腹水性质鉴别诊断的辅助指标。Objective To investigate the value of adenosine deaminase(ADA),carcino-embryonic antigen(CEA),total protein(TP),C-reactive protein(CRP)and cytology in the differential diagnosis of pleural effusion and ascites.Methods Determine CEA,ADA,TP,CRP and cytology of the pleural effusion and ascites in 273 patients with definite diagnosis,and make a statistical analysis.Results The white blood cell count of non-inflammatory group was lower than that of the other two groups(P<0.05),the proportion of lymphocytes in tuberculous group was higher than that of the other two groups(P<0.05),the proportion of mesothelial cells in malignant group was the highest,while that in tuberculous group was the lowest;the level of ADA,CRP in tuberculous group was higher than that of the other two groups(P<0.05),the CEA content in malignant group was higher than that in the other two groups(P<0.05),the TP content in tuberculous group and malignant group was higher than that in non-inflammatory group(P<0.05).Conclusion CEA,ADA,TP,CRP and cytology of pleural effusion can be used as auxiliary indexes for differential diagnosis of pleural effusion and ascites.

关 键 词：胸腔积液与腹水 腹水 腺苷脱氨酶 C反应蛋白 肿瘤 

分 类 号：R73[医药卫生—肿瘤]