四君子汤加减联合肠内营养对胃癌术后患者免疫功能的影响  

Effects of Sijunzi Decoction and Enteral Nutrition on Immune Function of Patients with Gastric Cancer after Operation

作　　者：李月红 LI Yue-hong(Chaoyang Central Hospital,Chaoyang 122000,China)

机构地区：[1]辽宁省朝阳市中心医院,辽宁朝阳122000

出　　处：《中国医药指南》2020年第19期152-153,共2页Guide of China Medicine

摘　　要：目的探讨评价四君子汤加减联合肠内营养对胃癌术后患者免疫功能的影响。方法选择我院2017年11月至2019年2月内收诊的110例胃癌患者作为对象,采用随机数表法按照1∶1比例将其分成对照组和研究组,各组占55例,对照组单纯给予肠内营养治疗,研究组则给予肠内营养+四君子汤加减治疗,观察两组患者术后恢复情况,并比较术前与术后的免疫功能。结果第一,研究组排气时间及住院时间短于对照组,差异显著,有统计学意义(P<0.05),而组间排便时间差异不大,无统计学意义(P>0.05)。第二,术前,组间IgG、IgA、CD4^+、CD8^+、CD4^+/CD8^+差异并无统计学意义(P>0.05),术后10 d两组患者各指标有所升高,且研究组IgG、IgA、CD4^+、CD4^+/CD8^+比对照组高,差异显著,有统计学意义(P<0.05)。结论胃癌患者,四君子汤加减联合肠内营养治疗,促进术后恢复,且可改善免疫功能,值得推广借鉴。Objective To evaluate the effect of Sijunzi Decoction plus enteral nutrition on immune function in patients with gastric cancer after operation.Methods 110 patients with gastric cancer admitted to our hospital from November 2017 to February 2019 were selected as subjects and randomly divided into control group and research group according to the ratio of 1∶1.Each group accounted for 55 cases.The control group was treated with enteral nutrition alone,while the research group was treated with enteral nutrition plus Sijunzi decoction.The recovery of patients in the two groups was observed and the preoperative and postoperative exemptions were compared.Epidemic function.Results Firstly,the exhaust time and hospitalization time of the study group were shorter than those of the control group,the difference was significant(P<0.05),but there was no significant difference in defecation time between the two groups(P>0.05).Secondly,there was no significant difference in IgG,IgA,CD4+,CD8+,CD4+/CD8+between the two groups before operation(P>0.05),and the indexes of the two groups increased 10 days after operation.The IgG,IgA,CD4+,CD4+/CD8+in the study group were higher than those in the control group,with significant difference(P<0.05).Conclusion Sijunzi Decoction combined with enteral nutrition can promote the recovery of patients with gastric cancer and improve the immune function,which is worthy of promotion and reference.

关 键 词：四君子汤加减 肠内营养 胃癌 术后 免疫功能 

分 类 号：R735.2[医药卫生—肿瘤]