脑梗死他汀类药物二级预防依从性的影响因素分析  

Analysis of Influencing Factors of Compliance with Secondary Prevention of Statins in Cerebral Infarction

作　　者：郭锡明 陈建荣[2] GUO Xi-ming;CHEN Jian-rong(Outpatient Department of Municipalities in Nantong City,Nantong 226001,Jiangsu,China;Department of Internal Medicine,the Affiliated Hospital of Nantong University,Nantong226001,Jiangsu,China)

机构地区：[1]江苏省南通市市级机关门诊部,江苏南通226001 [2]江苏省南通大学附属医院分院内科,江苏南通226001

出　　处：《医学信息》2020年第13期151-153,共3页Journal of Medical Information

摘　　要：目的分析脑梗死二级预防中他汀药物应用依从性的影响因素。方法回顾性分析2017年1月~2019年6月南通市市级机关门诊部及南通大学附属医院收治的138例他汀药物二级预防的脑梗死患者,根据他汀依从性判断标准将依从性差的87例患者作为观察组,将依从性好的51例患者作为对照组,比较两组临床资料,并采用多因素Logistic回归分析他汀药物应用依从性的影响因素。结果两组性别比较,差异无统计学意义(P>0.05);两组年龄、地域来源、文化程度、血脂水平、NIHSS评分、脑梗死病程、用药种类、经济收入、家属支持、医患关系、二级预防认知、他汀不良反应情况比较,差异有统计学意义(P<0.05)。Logistic回归分析显示,二级预防认知不足、经济收入低、他汀药物不良反应、年龄>70岁是脑梗死二级预防他汀药物依从性的影响因素。结论脑梗死二级预防应用他汀类药依从性差,影响因素较多,应及时准确评估导致依从性差的影响因素,采取相应措施提高依从性。Objective To analyze the influencing factors of statins compliance in the secondary prevention of cerebral infarction.Methods A retrospective analysis of 138 cases of cerebral infarction patients with secondary prevention of statins treated in the outpatient department of Nantong City Municipal Office and Nantong University Affiliated Hospital from January 2017 to June 2019,according to the statin compliance judgment criteria,87 patients with poor compliance were used as the observation group,and 51 patients with good compliance were used as the control group.The clinical data of the two groups were compared,and the influencing factors of statin drug compliance were analyzed using multivariate Logistic regression.Results There was no statistically significant difference between the two groups in gender(P>0.05);The difference between the two groups in age,geographical origin,education,blood lipid level,NIHSS score,course of cerebral infarction,type of medication,economic income,family support,doctor-patient relationship,secondary prevention cognition,and statin adverse reactions were statistically significant(P<0.05).Logistic regression analysis showed that insufficient prevention of secondary prevention,low economic income,adverse effects of statins,and age>70 years were the influencing factors of compliance with statins for secondary prevention of cerebral infarction.Conclusion The secondary prevention of cerebral infarction uses statins with poor compliance and many influencing factors.It is necessary to promptly and accurately assess the influencing factors that lead to poor compliance and take corresponding measures to improve compliance.

关 键 词：脑梗死 他汀类药物 二级预防 依从性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]