用于牙周炎治疗的自噬调节物研究现状  

Research Progress of Autophagy Regulators for Periodontitis Treatment

作　　者：齐晓爽[1,2] 孟维艳 QI Xiaoshuang;MENG Weiyan(Department of Dental Implantology, School and Hospital of Stomatology, Changchun 130021, China;Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Jinlin University, Changchun 130021, China)

机构地区：[1]吉林大学口腔医院口腔种植中心,吉林长春130021 [2]吉林省牙发育及颌骨重塑与再生重点实验室,吉林长春130021

出　　处：《口腔医学研究》2020年第7期616-618,共3页Journal of Oral Science Research

基　　金：国家自然科学基金(编号:81571007)。

摘　　要：牙周炎是口腔中发病率较高,并且与全身健康密切相关的自身免疫反应,然而对于牙周炎的治疗目前并无统一标准。细胞自噬是机体自身抵抗外来疾病的防御机制,近年来利用细胞自噬在宿主防御牙周炎驱动因素中的作用,为治疗牙周炎提供新思路。本文针对几种具有治疗牙周炎作用的自噬调节物的研究现状作一综述。Periodontitis is an autoimmune response with a high incidence in oral cavity and closely related to general health.However,there is no uniform standard for the treatment of periodontitis.Cell autophagy is the body's own defense mechanism against foreign diseases.In recent years,the role of autophagy in the host defense of periodontitis is used to provide a new way for the treatment of periodontitis.This article reviews the research status of several autophagy regulators with therapeutic effect on periodontitis.

关 键 词：牙周炎 自噬调节 

分 类 号：R78[医药卫生—口腔医学]