异种脱细胞真皮基质、异体脱细胞真皮基质与自体皮瓣修复颌面部软组织缺损疗效对比  

A Comparative Study on the Effects of Xenogeneic Acellular Dermal Matrix,Allogeneic Acellular Dermal Matrix and Autologous Skin Flap in the Repair of Soft Tissue Defects of Oral and Maxillofacial

作　　者：胡琼方 胡永琼 梅时友 HU Qiong-fang;HU Yong-qiong;MEI Shi-you(Department of Stomatology,Chongqing Three Gorges Center Hospital,Chongqing 404000,China)

机构地区：[1]重庆三峡中心医院口腔内科,重庆404000

出　　处：《中国美容医学》2020年第7期61-64,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:对比异种脱细胞真皮基质、异体脱细胞真皮基质与自体皮瓣修复颌面部软组织缺损的临床效果。方法:收集76例颌面部软组织缺损患者的临床资料,26例进行异种脱细胞真皮基质修复术(异种组),25例进行异体脱细胞真皮基质修复术(异体组),25例进行自体皮瓣修复术(自体组)。对比三组患者住院时间、术后疼痛程度、移植物成活率及术后并发症。结果:异种组和异体组住院时间均短于自体组(P<0.05),且异种组和异体组相比无统计学差异(P>0.05);异种组和异体组VAS疼痛评分均低于自体组(P<0.05),且异种组和异体组相比无统计学差异(P>0.05);三组患者移植物成活率相比,差异无统计学意义(P>0.05),异种组并发症发生率低于自体组(P<0.01)。结论:在颌面部软组织缺损修复中,异种脱细胞真皮基质、异体脱细胞真皮基质具有与自体皮瓣相当的移植物成活率,且异种ADM和异体ADM能够减轻患者术后疼痛程度,减少并发症发生,缩短住院时间,安全可靠。Objective To compare the clinical effect of xenogeneic acellular dermal matrix,allogeneic acellular dermal matrix and autologous skin flap in the repair of soft tissue defects of oral and maxillofacial.Methods The clinical data of 76 patients with soft tissue defects of oral and maxillofacial were collected,among which 26 cases treated with xenogeneic acellular dermal matrix repair were recorded as xenogeneic group,25 cases treated with allogeneic acellular dermal matrix repair were recorded as allogeneic group,and 25 cases were treated with autogenous skin flap repair were recorded as autogenous group.The length of stay,postoperative pain,graft survival rate and postoperative complications were compared among the three groups.Results The hospitalization time of the xenogeneic group and the allogeneic group was shorter than that of the autogeneic group(P<0.05),and there were no significant difference between the xenogeneic group and the allogeneic group(P>0.05).The VAS pain scores of the xenogeneic group and the allogeneic group were lower than that of the autogenous group(P<0.05),and there were no significant difference between the xenogeneic group and the allogeneic group(P>0.05).There were no significant difference in the survival rate of the three groups(P>0.05).The incidence of complications in the heterologous group was lower than that in the autogenous group(P<0.01).Conclusion In the repair of soft tissue defects of oral and maxillofacial,xenogeneic ADM and allogeneic ADM have graft survival rates comparable to autologous skin flaps,and heterogeneous ADM and allogeneic ADM can reduce postoperative pain,reduce complications,shorten hospital stays,safe and reliable.

关 键 词：脱细胞真皮基质 自体皮瓣 口腔颌面部 软组织缺损 修复 

分 类 号：R782.2[医药卫生—口腔医学]