兰州市8~10岁儿童甲状腺肿大现况调查分析  

A Prevalence Survey of Thyroid Enlargement in Children Aged 8 to 10 Years in Lanzhou,Gansu Province

作　　者：杨新建[1] 李普[1] 李盛 王辉[3] 王金玉[4] 李珍珍[3] 高金霞[3] 郑艳妮 YANG Xinjian;LI Pu;LI Sheng;WANG Hui;WANG Jinyu;LI Zhenzhen;GAO Jinxia;ZHENG Yanni

机构地区：[1]白银市第二人民医院,甘肃省白银市730900 [2]兰州市第一人民医院 [3]兰州市疾病预防控制中心 [4]兰州大学基础医学院

出　　处：《环境卫生学杂志》2020年第2期138-142,共5页JOURNAL OF ENVIRONMENTAL HYGIENE

基　　金：兰州市科技计划资助项目(2018-1-121,2019-RC-70);兰州市城关区科技计划资助项目(2017SHFZ0037)。

摘　　要：目的分析兰州市(8~10)岁儿童甲状腺肿大情况,了解儿童碘摄入情况。方法于2016年按照甘肃省碘缺乏病监测方案,在兰州市8个区(县)分层整群随机抽取43所小学,每个区(县)随机抽取(8~10)岁学生200名(共1600名)作为研究对象,收集年龄、性别、甲状腺容积、尿碘化物和碘盐等相关资料。结果1600名(8~10)岁儿童甲状腺容积中位数M为3.95 m L,甲状腺肿大率为3.25%,男性儿童甲状腺容积中位数高于女性儿童(P<0.01)。不同性别和不同年龄间甲状腺肿大率及不同年龄儿童甲状腺容积中位数均无统计学差异(P>0.05)。碘盐M为23.80 mg/kg,合格碘盐率为93.06%,不同性别和不同年龄碘盐摄入量均无统计学差异(P>0.05)。合格碘盐组甲状腺容积中位数低于不合格碘盐组和非碘盐组,不同碘盐水平下甲状腺容积中位数和甲状腺肿大率差异均无统计学意义(P>0.05)。尿碘化物中位数为190.00μg/L,男性尿碘化物含量高于女性(P<0.01)。不同年龄组间尿碘化物含量无统计学差异(P>0.05),儿童尿碘化物与甲状腺容积呈正相关。结论兰州市(8~10)岁儿童碘营养总体处于适宜水平,甲状腺容积与碘营养状况相关。Objective To investigate the prevalence rate of thyroid enlargement in children aged(8~10)years in Lanzhou,Gansu province and its influencing factors.Methods In 2016,according to the iodine deficiency disorders surveillance program of Gansu province,43 primary schools were selected from eight districts(counties)in Lanzhou using the stratified cluster sampling method,and 200 students(1600 in total)aged(8~10)years were randomly selected from each district(county)as subjects.The relevant data such as age,gender,thyroid volume,urinary iodine content,and iodine content in iodized salts were collected.Results The median thyroid volume of the 1600 children was 3.95 mL,and the goiter rate was 3.25%;male children had a significantly higher median thyroid volume than female children(P<0.01).There were no significant differences between thyroid volume,different genders and ages of children(P>0.05).The median iodine content in iodized salts was 23.80 mg/kg,with a qualified rate of 93.06%;there were no significant differences in iodized salt intake between different gender and age(both P>0.05).The median thyroid volume of qualified iodized salt group was lower than that of unqualified iodized salt and non-iodized salt groups.The median urinary iodine content was190.00μg/L,and male children had a significantly higher value than female children(P<0.01).There was no significant differences in urinary iodine content between different age groups(P>0.05).There was a positive correlation between urinary iodine content and thyroid volume in children.Conclusion Iodine nutrition is generally at an appropriate level in children aged(8~10)years in Lanzhou.Thyroid volume is correlated with iodine nutritional status.

关 键 词：甲状腺容积 碘盐 尿碘化物 儿童 

分 类 号：R12[医药卫生—环境卫生学]