种植体引起双膦酸盐相关性下颌骨坏死1例  

Bisphosphonate-related osteonecrosis of the jaw caused by implant:a case report

作　　者：吴平凡[1] 李羽[1] 雷振革 陈林林[1] Wu Pingfan;Li Yu;Lei Zhenge;Chen Linlin(Affiliated Stomatological Hospital of Nanchang University,The Key Laboratory of Biomedicine of Jiangxi Province,Nanchang 330006,China)

机构地区：[1]南昌大学附属口腔医院,江西省口腔生物医学重点实验室,南昌330006

出　　处：《华西口腔医学杂志》2020年第4期460-463,共4页West China Journal of Stomatology

基　　金：江西省卫生计生委科技计划(20171096)。

摘　　要：随着双膦酸盐类药物在骨质疏松、恶性肿瘤骨转移等方面的广泛应用,不断有颌骨坏死发生的报道,已逐渐引起口腔医生的高度关注。本文报道1例种植体植入术后引起双膦酸盐相关性颌骨坏死的病例,并结合相关文献阐述双膦酸盐类药物性颌骨坏死的发病机制、诊断、预防及治疗方法,进一步讨论使用双膦酸盐后对种植体的影响。Osteonecrosis of the jaw could occur after intake of bisphosphonate drugs,which are widely used to treat osteoporosis and bone metastasis of malignant tumors.This effect has aroused concern among dentists.In this paper,a case of bisphosphonate-related osteonecrosis caused by implant is reported,and the pathogenesis,diagnosis,prevention,and treatment of bisphosphonate drug-induced osteonecrosis are described through a literature review.The effects of bisphosphonate drug treatment on dental implants are also discussed.

关 键 词：双膦酸盐 骨坏死 颌骨 种植体 

分 类 号：R782.3[医药卫生—口腔医学]