泪腺良性淋巴上皮病变诊断与治疗的研究进展  

Advances on the diagnosis and treatment of benign lymphoepithelial lesions of lacrimal gland

作　　者：栾福晓 马建民 Luan Fuxiao;Ma Jianmin(Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;Beijing Tongren Eye Center,Beijing Tongren hospital,Capital Medical University,Beijing Institute of Ophthalmology,Beijing Key Laboratory of Ophthalmology and Visual Sciences,Beijing 100730,China)

机构地区：[1]首都医科大学附属北京同仁医院,100730 [2]首都医科大学附属北京同仁医院,北京同仁眼科中心,北京市眼科研究所,眼科学与视觉科学北京市重点实验室,100730

出　　处：《中华眼科医学杂志（电子版）》2020年第3期188-192,共5页Chinese Journal of Ophthalmologic Medicine(Electronic Edition)

基　　金：北京市自然基金项目(7182038);北京市医院管理中心"登峰"计划专项项目(DFL20190201)。

摘　　要：泪腺良性淋巴上皮病变(LGBLEL)是一种眼眶疾病,主要的临床表现为双眼或单眼无痛性泪腺肿大和眼睑肿胀。目前,LGBLEL的病因与发生机制尚不明确,暂无统一的诊断标准与治疗方案。LGBLEL患者的病情反复,迁延不愈,且病情具有恶变的倾向。因此,LGBLEL的早期准确诊断和早期合理而规范地治疗尤为重要。本文中笔者就近年来国内外LGBLEL的临床表现、影像学特征、实验室检测指标和病理组织学特点等疾病诊断的相关内容,以及LGBLEL的糖皮质激素治疗、手术切除辅以糖皮质激素治疗和放射治疗等各种治疗方式的研究进展进行综述,旨在为合理规范地诊断和治疗LGBLEL提供参考。Benign lymphoepithelial lesions of lacrimal gland(LGBLEL)is a type of orbital disease characterized by painless enlargement of lacrimal gland(s)and swelling of the eyelid(s)in both eyes or one eye.Up to now,its etiology and pathogenesis have not been clarified and unified diagnostic standard and treatment therapy for LGBLEL patients as well have not been developed.LGBLEL can appear to be recurrent and unsustainable,which has a tendency to malignant transformation.Therefore,it was particularly important for early accurate diagnosis and reasonable standardized treatment of the disease.This article will focus on studies of the clinical manifestations,imaging characteristics,laboratory test indicators,histopathological characteristics and treatment methods such as glucocorticoid therapy,radiotherapy,surgical resection with glucocorticoid therapy of LGBLEL in recent years at home and abroad.Summarizing the mentioned above is aim to provide the reference for the diagnosis and treatment of LGBLEL.

关 键 词：泪腺 良性淋巴上皮病变 诊断 治疗 

分 类 号：R777.21[医药卫生—眼科]