血清总胆汁酸与传统肝功能酶学指标在肝胆疾病中的诊断价值  

Diagnostic Value of Serum Total Bile Acid and Traditional Liver Function Enzyme Index in Hepatobiliary Diseases

作　　者：张炳森 ZHANG Bing-sen(Department of Clinical Laboratory,Dandong First Hospital,Dandong 118000,China)

机构地区：[1]丹东市第一医院检验科,辽宁丹东118000

出　　处：《中国医药指南》2020年第20期166-167,共2页Guide of China Medicine

摘　　要：目的探讨血清总胆汁酸与传统肝功能酶学指标在肝胆疾病中的诊断价值。方法研究共选择45例肝胆疾病患者作为研究资料,包含急性肝炎15例,肝硬化15例,肝癌15例,另选择45例健康体检者作为对照组,均于本院2016年7月至2018年7月期间接收,均行血清总胆汁酸与传统肝功能酶学指标检测,并进行组间比较。结果对照组ALT、AST、ALP、GGT、TBA等均显著低于急性肝炎患者、肝硬化患者和肝癌患者,P<0.05;而且急性肝炎患者与肝硬化患者、肝癌患者各指标比较差异显著,P<0.05;肝硬化患者TBA、AST、ALP、GGT显著低于肝癌患者,P<0.05;急性肝炎、肝硬化和肝癌患者TBA阳性率100.0%,100.0%,93.33%,均显著高于ALT、AST、ALP、GGT阳性率,P<0.05。结论传统肝功能酶学指标检测可起到检出肝胆疾病作用,而辅助血清总胆汁酸可进一步提高阳性率,且可作为鉴别不同肝胆疾病的依据,应用价值较高。Objective To investigate the diagnostic value of serum total bile acid and traditional liver function enzymes in hepatobiliary diseases.Methods A total of 45 patients with hepatobiliary diseases were selected as research data,including 15 cases of acute hepatitis,15 cases of liver cirrhosis,15 cases of liver cancer,and 45 cases of healthy subjects as control group.All of them were in our hospital from July to 20,2016.During the period of July,the serum total bile acid and traditional liver function enzyme indicators were tested and compared between groups.Results The ALT,AST,ALP,GGT and TBA in the control group were significantly lower than those in acute hepatitis patients,liver cirrhosis patients and liver cancer patients,P<0.05.Moreover,the indicators of acute hepatitis patients and liver cirrhosis patients and liver cancer patients were significantly different,P<0.05;TBA,AST,ALP,GGT in patients with cirrhosis were significantly lower than those in patients with liver cancer,P<0.05;TBA positive rate in patients with acute hepatitis,cirrhosis and liver cancer was 100.0%,100.0%,93.33%,both significantly higher than ALT,AST,ALP,GGT positive rate,P<0.05.Conclusion Strengthening the detection of serum total bile acids and traditional liver function enzymes can detect the effects of hepatobiliary diseases,and can be used as a basis for identifying different hepatobiliary diseases.

关 键 词：血清总胆汁酸 肝功能酶学指标 肝胆疾病 

分 类 号：R575[医药卫生—消化系统]