真空带式干燥与喷雾干燥的灵芝皇粉体性质对比  

Quality Comparison of Ganoderma Lucidum Powder by Vacuum Belt Drying and Spray Drying

作　　者：周代营[1] 张欣 聂阳[1] 刘卫海[1] 丁立[1] 李德灵 ZHOU Daiying;ZHANG Xin;NIE Yang;LIU Weihai;DING Li;LI Deling(School of Pharmaceutical Engineering,Guangdong Food and Drug Vocational College,Guangzhou 510520,China;Infinitus International(China)SdnBhd,Jiangmen 529100,China)

机构地区：[1]广东食品药品职业学院制药工程学院,广州510520 [2]无限极中国有限公司,江门529100

出　　处：《医药导报》2020年第8期1125-1128,共4页Herald of Medicine

基　　金：国家自然科学基金资助项目(81272452);广东省自然科学基金资助项目(2014A030310329)。

摘　　要：目的比较真空带式干燥与喷雾干燥工艺优劣势,制定灵芝皇粉干燥工艺优化方案。方法以灵芝皇为试材,比较真空带式干燥与喷雾干燥对灵芝皇粉体品质的影响。结果真空带式干燥粉体与喷雾干燥粉体相比休止角小,流动性好,粒径小,含水量低,溶解快,松密度大。扫描电镜图片显示带式干燥灵芝皇粉外形不规则,而喷雾干燥粉外形多为囊泡状球形样品。吸湿性实验结果显示,带式干燥粉、喷雾干燥粉的吸湿接近平衡时间分别为36,72 h,达到平衡时间为72,96 h,带式干燥粉、喷雾干燥粉的临界相对湿度(CRH)分别为67.34%,75.40%。结论相对于喷雾干燥粉,带式干燥粉吸湿达平衡时间短,吸湿性较小,易于保存。且带式干燥制成的粉体不易吸湿,流动性好。Objective Compare the advantages and disadontages of two kinds Ganoderma lucidum powders and fromulate drying process optimization scheme.Methods The quality of two kinds of Ganoderma lucidum powders produced by vacuum belt drying and spray drying were compared.Results Compared with spray dry powder,vacuum belt dry powder has smaller repose angle,better fluidity,smaller particle size,lower water content,faster dissolution,and higher bulk density.Scanning electron microscopy showed that the shape of Ganoderma lucidum powder with dry powder was irregular,while the shape of spray powder was mostly spherical and vesicular.The results of the hygroscopic experiment showed that the time of approaching hygroscopic equilibrium was 36 and 72 h with dry powder and spray dry powder respectively,and the time of reaching equilibrium was 72 and 96 h,and the CRH with dry powder and spray dry powder were 67.34%and 75.40%respectively.Conclusion Compared with spray dry powder,the time for moisture absorption to reach equilibrium is shorter,and the moisture absorption is smaller,so it is easy to preserve.Therefore,the powder made by belt drying is not easy to absorb moisture and has good fluidity.

关 键 词：灵芝皇粉体 带式干燥 喷雾干燥 

分 类 号：R943[医药卫生—药剂学]