急性黄斑旁中心中层视网膜病变研究进展  

Research progress on paracentral acute middle maculopathy

作　　者：许领先 王晨光[1] 苏冠方[1] XU Lingxian;WANG Chenguang;SU Guanfang(Department of Ophthalmology,the Second Hospital of Jilin University,Changchun 130022,Jilin Province,China)

机构地区：[1]吉林大学第二医院眼科中心,吉林省长春市130022

出　　处：《眼科新进展》2020年第8期784-788,共5页Recent Advances in Ophthalmology

摘　　要：急性黄斑旁中心中层视网膜病变(paracentral acute middle maculopathy,PAMM)是一类以突发的旁中心暗点为特征的黄斑区中层视网膜病变,其特点为光学相干层析成像(spectral-domain optical coherence tomography,SD-OCT)上的内核层(inner nuclear layer,INL)高反射条带。目前该病病因及发病机制尚不十分清楚,多数研究认为其与视网膜中层毛细血管网(intermediate capillary plexus,ICP)和视网膜深层毛细血管网(deep capillary plexus,DCP)缺血密切相关。自首次报道以来,随着多模式成像技术的不断发展,研究者对该病变的认识也不断深入。本文将对PAMM的临床特征、可能的发病机制和罹患因素的研究进展进行综述。Paracentral acute middle maculopathy(PAMM)is a kind of abnormalities of the middle retina in the macula characterized by acute onset of paracentral scotomas.It is characterized by the hyperreflective band-like lesions at the level of the inner nuclear layer(INL)on spectral-domain optical coherence tomography(SD-OCT).At present,the etiology and pathogenesis of this entity are not very clear.Most researches suggest that it is closely related to the ischemia of intermediate capillary plexus(ICP)and deep capillary plexus(DCP).Advances in multimodal imaging have enabled a greater understanding of this retinal disorder since it was first described.This article aims to review the clinical features,possible pathogenic mechanisms and risk factors of PAMM.

关 键 词：急性黄斑旁中心中层视网膜病变 临床特征 发病机制 

分 类 号：R774.1[医药卫生—眼科]