重症肌无力患者针极肌电图肌源性损害表现的相关研究  

Correlative study on the myogenic damage of needle electrode electromyography in patients with myasthenia gravis

作　　者：冯淼玲[1] 魏统国[1] 许伟[1] 邹友权[1] FENG Miaoling;WEI Tongguo;XU Wei;ZOU Youquan(Department of Three Neurology,Meizhou People's Hospital,Guangdong,Meizhou 514000,China)

机构地区：[1]广东省梅州市人民医院神经内三科,广东梅州514000

出　　处：《中国医药科学》2020年第13期217-219,共3页China Medicine And Pharmacy

基　　金：广东省梅州市医药卫生科研课题(2017-B-34)。

摘　　要：目的探讨重症肌无力患者针电极肌电图的检查结果,以及与肌源性损害表现的相关性。方法随机选取我院2016年1月~2019年1月收治的确诊为重症肌无力患者80例,进行针电极肌电图检查,比较患者的不同临床表现。结果针电极肌电图正常率明显低于重复神经电刺激正常率(P<0.05),即针电极肌电图检查的准确率显著高于重复神经电刺激;不同Osserman分型,患者肌源性损害表现差异无统计学意义(P>0.05),即肌源性损害表现与Osserman分型无相关性;无肌源性受损表现组以眼外肌无力为首发症状的患者最多,而有肌源性受损表现组以肢体和球部肌肉起病为多,两者比较差异有统计学意义(P<0.05)。结论重症肌无力患者应用针电极肌电图检查,准确度高,能够在一程度上显示病情的严重性。Objective To explore the examination results of needle electrode electromyography(NEMG)in patients with myasthenia gravis(MG)and its correlation with the manifestations of myogenic damage.Methods 80 patients with MG diagnosed and admitted in our hospital from January 2016 to January 2019 were randomly selected.NEMG was performed for all patients,and the clinical manifestations were compared between those patients.Results The normal rate of the NEMG was significantly lower than that of repetitive nerve stimulation(RNS)(P<0.05),namely,the examination accuracy of the NEMG was significantly higher than that of RNS;there was no difference in myogenic damage between different Osserman types(P>0.05),namely,there was no correlation between manifestations of myogenic damage and Osserman types;extraocular muscle weakness was the original symptom in group with no myogenic damage,while the onset of limb and ball muscles was common in group with myogenic damage,and the difference was statistically significant(P<0.05).Conclusion NEMG for patients with MG has high examination accuracy and can show the severity of the disease to a certain extent.

关 键 词：重症肌无力 针电极肌电图 肌源性损害 临床表现 

分 类 号：R746.1[医药卫生—神经病学与精神病学]