Ubiquitin:there’s no quitting  

病原菌劫持宿主泛素系统以逃避免疫反应

作　　者：Abdullah F.U.H.Saeed Songying Ouyang 阿卜杜拉;欧阳松应(The Key Laboratory of Innate Immune Biology of Fujian Province,Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation,Biomedical Research Center of South China,Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education,College of Life Sciences,Fujian Normal University,Fuzhou 350117,China;Laboratory for Marine Biology and Biotechnology,Pilot National Laboratory for Marine Science and Technology(Qingdao),Qingdao 266237,China;College of Chemistry and Materials Science,Fujian Normal University,Fuzhou 350117,China)

机构地区：[1]The Key Laboratory of Innate Immune Biology of Fujian Province,Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation,Biomedical Research Center of South China,Key Laboratory of Optoelectronic Science and Technology for Medicine of Ministry of Education,College of Life Sciences,Fujian Normal University,Fuzhou 350117,China [2]Laboratory for Marine Biology and Biotechnology,Pilot National Laboratory for Marine Science and Technology(Qingdao),Qingdao 266237,China [3]College of Chemistry and Materials Science,Fujian Normal University,Fuzhou 350117,China

出　　处：《Science Bulletin》2020年第16期1327-1329,M0003,共4页科学通报（英文版）

基　　金：the Special Open Fund of Key Laboratory of Experimental Marine Biology,Chinese Academy of Sciences(SKF2020NO1);the National Natural Science Foundation of China(31770948,and 31570875);the Highlevel Personnel Introduction Grant of Fujian Normal University(Z0210509);Marine Economic Development Special Fund of Fujian Province(FJHJF-L-2020-2)。

摘　　要：Innate immunity is the first line of defense against pathogens in the host cells,which include neutrophils,monocytes,macrophages,eosinophils,mast cells,dendritic cells,and so on.However,in what way these cells have changed the innate immune responses stays unclear.The immune system is complex and protects from countless diseases.It uses pattern-recognition receptors(PRRs)to recognize evolutionary conserved pathogen-associated molecular patterns(PAMPs)from pathogens[1].Innate immunity is the first line of defense against pathogens in the host cells,which include neutrophils,monocytes,macrophages,eosinophils,mast cells,dendritic cells,and so on.However,in what way these cells have changed the innate immune responses stays unclear.The immune system is complex and protects from countless diseases.It uses pattern-recognition receptors(PRRs)to recognize evolutionary conserved pathogen-associated molecular patterns(PAMPs)from pathogens[1].

关 键 词：免疫反应 IMMUNITY PATTERN 

分 类 号：R378[医药卫生—病原生物学]