视网膜激光光凝术治疗对眼底病患者黄斑区视网膜厚度及中心凹容积的影响  

Effect of retinal laser photocoagulation on macular retinal thickness and foveal volume in patients with fundus disease

作　　者：朱巧平 王乾[1] ZHU Qiao-ping;WANG Qian(Department of Ophthalmology,the First Hospital of Yulin,Yulin 719000,Shaanxi,CHINA)

机构地区：[1]榆林市第一医院眼科,陕西榆林719000

出　　处：《海南医学》2020年第14期1850-1852,共3页Hainan Medical Journal

摘　　要：目的探讨视网膜激光光凝术对眼底病患者黄斑区视网膜厚度及中心凹容积的影响。方法选择2018年1月至2019年1月榆林市第一医院眼科收治的眼底病患者84例作为研究对象,按随机数表法分为对照组(42例,71眼)和观察组(42例,68眼)。对照组采用沃丽汀药物治疗,观察组在对照组治疗的基础上联合视网膜激光光凝术治疗,两组均完成2个月治疗,并完成12个月随访。比较两组患者的黄斑区视网膜厚度、中心凹容积、视力水平、并发症发生率及复发率。结果黄斑区视网膜厚度和中心凹容积分别为(312.53±15.79)μm、(8.96±1.35)mm^3,明显大于对照组的(302.56±14.32)μm、(8.54±1.30)mm^3,差异均有统计学意义(P<0.05);观察组患者治疗后2个月的视力提高率为66.18%,明显高于对照组的47.89%,视力下降率为5.88%,明显低于对照组的16.90%,差异均有统计学意义(P<0.05);两组患者治疗后1个月的复发率均为0,观察组患者治疗后6个月、12个月的复发率分别为2.38%、4.76%,明显低于对照组的11.90%和19.05%,差异均有统计学意(P<0.05);观察组与对照组并发症发生率比较差异无统计学意义(P>0.05)。结论视网膜激光光凝术应用于眼底病能改善患者黄斑区视网膜厚度、中心凹容积,提高其视力水平,未增加并发症发生率,能降低治疗后复发率,值得推广应用。Objective To explore the effect of retinal laser photocoagulation on macular retinal thickness and the foveal volume in patients with fundus disease.Methods A total of 84 patients with ocular fundus disease in the First Hospital of Yulin from January 2018 to January 2019 were selected as the research objects.They were divided into control group(n=42,71 eyes)and an observation group(n=42,68 eyes).The control group was treated with voretine,and the observation group was treated with retinal laser photocoagulation on the basis of the control group.Two months of treatment and 12 months follow-up were completed in both groups.The macular retinal thickness,foveal volume,visual acuity level,complication rate,and recurrence rate were compared between the two groups.Results Two months after treatment,the macular retinal thickness and the foveal volume in the observation group were(312.53±15.79)μm and(8.96±1.35)mm^3,which were significantly greater than(302.56±14.32)μm and(8.54±1.30)mm^3 in the control group(P<0.05).After 2 months of treatment,the improvement rate of visual acuity in the observation group was66.18%,which was significantly higher than 47.89%in the control group,and the decrease rate of visual acuity was5.88%,which was significantly lower than 16.90%in the control group(P<0.05).The relapse rate of the two groups after 1 month of treatment was 0,and the relapse rate in the observation group after 6 months and 12 months of treatment were 2.38%and 4.76%,which were significantly lower than 11.90%and 19.05%in the control group(P<0.05).There were no significant difference in the incidence of complications between the observation group and the control group(P>0.05).Conclusion Retinal laser photocoagulation can improve the macular retinal thickness,foveal volume,and visual acuity level of patients with fundus diseases,and can reduce the recurrence rate after treatment,without increasing the incidence of complications,which is worthy of popularization and application.

关 键 词：视网膜激光光凝术 眼底病 黄斑区视网膜厚度 中心凹容积 视力水平 复发率 

分 类 号：R771[医药卫生—眼科]