阿尔茨海默病物理治疗的作用机制及应用  

Mechanism and Application of Physical Therapy for Alzheimer's Disease

作　　者：杨金菊 邹显巍[2] 余建萍[2] 刘晓蕾 徐帆 Yang Jinju;Zou Xianwei;Yu Jianping;Liu Xiaolei;Xu fan(College of Pharmacy,Chengdu Medical College,Chengdu 610500,China;The first Affiliated Hospital of Chengdu Medical College,Chengdu 610500,China;Department of Neurology,the Affiliated Hospital of Kunming Medical University,Kunming 646000,China;College of Public Health,Chengdu Medical College,Chengdu 610500,China)

机构地区：[1]成都医学院药学院,成都610500 [2]成都医学院第一附属医院,成都610500 [3]昆明医科大学附属医院神经内科,昆明646000 [4]成都医学院公共卫生学院,成都610500

出　　处：《国际老年医学杂志》2020年第4期262-265,共4页International Journal of Geriatrics

基　　金：成都医学院自然科学基金(CYZ18-33);四川大学生创新创业项目(S201913705080,S201913705130,S201913705059)。

摘　　要：阿尔茨海默病(Alzheimer′s disease,AD)是由各种因素引起的一种神经系统退行性疾病。患者可出现认知功能丧失、执行功能障碍、记忆障碍、失语症以及行为和人格改变等痴呆表现,AD的病因目前还在探索中。现在用于AD治疗的有效药物不多,研究比较多的是物理治疗,最主要的方式包括光线疗法、经颅直流电刺激和重复经颅磁刺激疗法,都能够在一定程度上改善AD的症状。本文以AD的这3种治疗方式展开综述,为日后该疾病治疗提供参考依据。Alzheimer′s disease(AD)is a neurodegenerative disease caused by various factors.The patients may manifest some dementia symptoms such as cognitive loss,executive dysfunction,memory impairment,aphasia,and behavior and personality changes.The etiology of AD is still being explored.Currently,there are few drugs for the treatment of AD,but physical therapy has been widely studied.The main physical therapy includes light therapy,transcranial direct current stimulation and repetitive transcranial magnetic stimulation,which can improve the symptoms of AD.This article reviews these three treatments for AD.

关 键 词：阿尔茨海默病 作用机制 光线疗法 经颅直流电刺激 重复经颅磁刺激 

分 类 号：R749.16[医药卫生—神经病学与精神病学]