老年胃癌临床研究进展  

Advances in clinical research of gastric cancer in elderly patients

作　　者：刘静[1] 张俊[1] Liu Jing;Zhang Jun(Department of Oncology,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属瑞金医院肿瘤科,上海200025

出　　处：《实用肿瘤杂志》2020年第4期287-291,共5页Journal of Practical Oncology

基　　金：国家自然科学基金(81972707)。

摘　　要：胃癌是我国高发肿瘤,发病高峰年龄在60~70岁之间,老年患者是主要患病人群。由于缺乏专门针对老年胃癌患者开展的临床研究,目前的数据多来自于回顾性研究,或随机试验基于年龄的亚组分析,对真实世界中老年胃癌患者的治疗指导价值十分有限。本文综述了近年来关于老年胃癌患者围手术期治疗和转移性疾病的化疗、靶向及免疫治疗领域的进展,以为临床实践提供参考。Gastric cancer is a high-risk tumor in China, with a peak age of 60-70 years old, and elderly patients are the main patient group. Due to the lack of clinical research specifically for elderly patients with gastric cancer, the current data mostly come from retrospective studies or age-based subgroup analysis in randomized trials. The value of treatment guidance for middle-aged and elderly patients with gastric cancer in the real world is very limited. This article reviews the recent advances in the field of perioperative therapy and systemic treatment with chemotherapy, target agents or immunotherapy for metastatic disease in elderly patients with gastric cancer, to provide a reference for clinical practice.

关 键 词：胃癌 衰老 临床研究 

分 类 号：R735.2[医药卫生—肿瘤]