糖尿病短泪膜破裂时间型干眼患者的症状和体征分析  

Analysis of Symptoms and Signs of Diabetic Dry Eye Patients with Short Tear Film Rupture Time

作　　者：李玲 李越虹[2] LI Ling;LI Yuehong(Beijing Zhongguancun Hospital,Beijing 100190,China;不详)

机构地区：[1]北京市中关村医院,北京100190 [2]中国中医科学院西苑医院

出　　处：《中外医学研究》2020年第16期132-134,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研讨糖尿病短泪膜破裂时间型干眼患者的具体症状和体征。方法:从2018年3-11月笔者所在医院选取60例糖尿病短泪膜破裂时间型干眼患者作为观察组,另选取40例非糖尿病短泪膜破裂时间型干眼患者作为对照组,对比分析糖尿病短泪膜破裂时间型干眼患者的具体症状和体征。结果:两组眨眼频率及角膜荧光素钠染色评分比较差异无统计学意义(P>0.05),观察组SPEED评分高于对照组,差异有统计学意义(P<0.05);观察组平均脂质层厚度薄于对照组,睑板腺拍照评分高于对照组,差异均有统计学有意义(P<0.05)。结论:在干眼症患者中,有糖尿病病史的患者睑板腺缺失或短缩的程度更大,从而让平均脂质层厚度变得更薄,进一步导致泪膜破裂时间更短,在临床上值得研究探讨。Objective:To study and analyze the specific symptoms and signs of diabetic dry eyes with short tear film rupture time.Method:From March to November 2018,60 cases of diabetic short tear film rupture time dry eye patients were selected as the observation group,and 40 cases of non diabetic short tear film rupture time dry eye patients were selected as the control group.The specific symptoms and signs of diabetic short tear film rupture time dry eye patients were compared and analyzed.Result:There was no significant difference in blink frequency and corneal fluorescein sodium staining scores between the two groups (P>0.05),the SPEED score in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05).The mean lipid layer thickness in the observation group was thinner than that in the control group,and meibomian gland photography score was higher than that in the control group,the differences were statistically significant (P<0.05).Conclusion:In patients with xerophthalmia,the degree of loss or shortening of meibomian gland is greater in patients with a history of diabetes,which makes the average lipid layer thickness thinner and further leads to shorter tear film rupture time,which is worthy of clinical study.

关 键 词：短泪膜破裂时间 糖尿病 干眼 症状体征 

分 类 号：R777.34[医药卫生—眼科] R587.2[医药卫生—临床医学]