非酒精性脂肪肝病双源CT表现与血脂水平的相关性  

Correlation between Dual Source CT Findings and Blood Lipid Levels in Nonalcoholic Fatty Liver Disease

作　　者：陈松[1] 吴奇新 黄泽和[1] 陈立坚[1] 李敏 李伟雄 CHEN Song;WU Qixin;HUANG Zehe;CHEN Lijian;LI Min;LI Weixiong(The First People’s Hospital of Qinzhou,Qinzhou 535000,China;不详)

机构地区：[1]钦州市第一人民医院,广西钦州535000 [2]崇左市人民医院 [3]广西中医院大学第一附属医院 [4]广西医科大学第二附属医院

出　　处：《中外医学研究》2020年第20期52-54,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：广西壮族自治区卫生和计划生育委员会自筹经费科研课题项目(Z20170970)。

摘　　要：目的:探讨非酒精性脂肪肝病双源CT表现与血脂水平的相关性。方法:选取笔者所在医院2017年1月-2019年8月收治的200例非酒精性脂肪肝病患者作为脂肪肝组,另选取同期体检的正常人员60例作为参考组,两组分别行双源CT检查,测量肝/脾CT值、肝脏脂肪含量;同时行血脂分析,检测甘油三酯(TG)、总胆固醇(CHOL)、血清低密度脂蛋白(LDL)、血清高密度脂蛋白(HDL)、血清载脂蛋白AI、血清载脂蛋白B;分析CT值、肝脏脂肪含量与血脂水平的相关性。结果:脂肪肝组肝/脾CT值(0.74±0.21)HU,低于参考组的(1.21±0.15)HU,肝脏脂肪含量(28.46±8.96)%,高于参考组的(9.54±3.02)%,差异有统计学意义(P<0.05)。脂肪肝组TG、CHOL、LDL、血清载脂蛋白AI、血清载脂蛋白B均高于参考组,HDL水平低于参考组(P<0.05)。重度脂肪肝组肝/脾CT值低于中、轻度组,肝脏脂肪含量、TG、CHOL、LDL、血清载脂蛋白AI、血清载脂蛋白B均高于中、轻度组,HDL水平低于中、轻度组(P<0.05),中度脂肪肝组与轻度组的双源CT表现及血脂水平比较,差异有统计学意义(P<0.05)。肝/脾比值与TG、CHOL、LDL、血清载脂蛋白AI、血清载脂蛋白B水平呈负相关,与HDL呈正相关;肝脏脂肪含量与TG、CHOL、LDL、血清载脂蛋白AI、血清载脂蛋白B水平呈正相关,与HDL呈负相关。结论:非酒精性脂肪肝病患者双源CT表现与血脂水平关系密切,血脂水平会影响肝/脾CT值,结合双能量脂肪定量技术可判定脂肪肝的浸润程度,值得临床推广。Objective:To investigate the correlation between the dual source CT findings of non-alcoholic fatty liver disease and blood lipid level.Method:A total of 200 patients with nonalcoholic fatty liver disease admitted to our hospital from January 2017 to August 2019 were selected as the fatty liver group,and 60 normal persons in the same period were selected as the reference group.The two groups were examined by dual source CT respectively to measure the CT value of liver/spleen and the fat content of liver;at the same time,blood lipid analysis was carried out to detect the total cholesterol(CHOL)of triglyceride(TG)and serum low-density fat egg LDL,HDL,AI and B,and the correlation between CT value,liver fat content and blood lipid level was analyzed.Result:The CT value of liver/spleen in the fatty liver group was(0.74±0.21)HU,which was lower than(1.21±0.15)HU in the reference group,and the content of liver fat was(28.46±8.96)%,which was higher than(9.54±3.02)%in the reference group,the differences were statistically significant(P<0.05).TG,CHOL,LDL,apolipoprotein AI and apolipoprotein B in the fatty liver group were higher than those in the reference group,and HDL level was lower than that in the reference group(P<0.05).The CT value of liver/spleen in the severe fatty liver group was lower than that in the moderate and mild group,the content of liver fat,TG,CHOL,LDL,serum apolipoprotein AI,serum apolipoprotein B were higher than those in the moderate and mild group,the level of HDL was lower than that in the moderate and mild group(P<0.05).Comparison of dual source CT findings and blood lipid levels between moderate fatty liver group and mild group were significant differences(P<0.05).Liver/spleen ratio was negatively correlated with TG,CHOL,LDL,serum apolipoprotein AI and serum apolipoprotein B,and positively correlated with HDL;liver fat content was positively correlated with TG,CHOL,LDL,serum apolipoprotein AI and serum apolipoprotein B,and negatively correlated with HDL.Conclusion:The dual source CT findings o

关 键 词：非酒精性脂肪肝病 双源CT 血脂分析 相关性 

分 类 号：R575[医药卫生—消化系统] R816.5[医药卫生—内科学]