急性重症胰腺炎患者早期肠内外营养支持的临床价值  

Clinical Value of Early Enteral and Parenteral Nutrition Support in Patients with Severe Acute Pancreatitis

作　　者：钟平玉 ZHONG Pingyu(Longyan First Hospital Affiliated to Fujian Medical University,Longyan 364000,China)

机构地区：[1]福建医科大学附属龙岩第一医院,福建龙岩364000

出　　处：《中外医学研究》2020年第21期147-149,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨急性重症胰腺炎(SAP)患者早期肠内外营养支持的临床价值。方法:选取2017年6月-2019年6月笔者所在医院收治的SAP患者80例,将其依据随机数字表法分成对照组与观察组,每组40例。观察组行肠内营养支持(EN),对照组行肠外营养支持(PN)。比较两组支持前及支持3周后的空腹血糖、白蛋白、血红蛋白、胆固醇、血肌酐水平及住院时间、并发症发生情况和病死情况。结果:两组支持3周后营养状况均较支持前有明显改善,差异有统计学意义(P<0.05)。观察组空腹血糖下降幅度及血红蛋白升高幅度明显优于对照组,差异均有统计学意义(P<0.05)。观察组高血糖、感染、多器官功能不全发生率均明显低于对照组,差异有统计学意义(P<0.05)。观察组住院时间短于对照组,差异有统计学意义(P<0.05)。两组病死率比较差异无统计学意义(P>0.05)。结论:SAP患者给予EN,能改善其营养状况,减少并发症发生,缩短住院时间,临床应用价值突出。Objective:To explore the clinical value of early enteral and parenteral nutrition support in patients with severe acute pancreatitis(SAP).Method:A total of 80 patients with SAP admitted in our hospital from June 2017 to June 2019 were selected and divided into the control group and the observation group according to the random number table method,with 40 patients in each group.The observation group received enteral nutritional support(EN)and the control group received parenteral nutritional support(PN).Fasting blood glucose,albumin,hemoglobin,cholesterol,serum creatinine levels,length of hospital stay,incidence of complications,and mortality were compared between the two groups before and 3 weeks after support.Result:The nutritional status of the two groups after 3 weeks of support were significantly improved compared with those before support,the difference was statistically significant(P<0.05).The decrease of fasting blood glucose and the increase of hemoglobin in the observation group were significantly better than those in the control group,the differences were statistically significant(P<0.05).The incidence of hyperglycemia,infection and multi-organ dysfunction in the observation group were significantly lower than those in the control group,the difference was statistically significant(P<0.05).The length of hospital stay in the observation group was shorter than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in mortality between the two groups(P>0.05).Conclusion:EN for SAP patients can improve their nutritional status,reduce the incidence of complications,shorten the length of hospital stay,and has outstanding clinical application value.

关 键 词：急性重症胰腺炎 早期肠内营养支持 胃肠外营养支持 

分 类 号：R576[医药卫生—消化系统]