进行性对称性红斑角化症临床与遗传的研究进展  

Advances in clinical and genetic studies of progressive symmetric erythematosis

作　　者：罗育武[1] 周欣[1] Luo Yuwu;Zhou Xin(Guangzhou Institute of Dermatology,Guangzhou,Guangdong 510000,China)

机构地区：[1]广州市皮肤病防治所皮肤科,广东广州510000

出　　处：《医药前沿》2020年第13期24-25,共2页Journal of Frontiers of Medicine

基　　金：皮肤病基因组计划前期研究项目(项目名称:进行性对称性红斑角化症的基因突变研究)。

摘　　要：红斑角化症属于以广泛分布角化性红斑作为临床特征的疾病,这一疾病多数情况下都伴随掌跖角化等情况,疾病包含着其进行性对称性红斑角化症和可变性红斑角化症两种临床亚型,进行性对称性红斑角化症(PSEK)也称为对称性进行性先天性红皮症疾病,其属于常染色体显性遗传性皮肤疾病。本文对进行性对称性红斑角化症研究进展进行综述。Erythema keratinization disease belong to widely distributed cornification sex erythema as clinical characteristics of the disease,this disease are mostly associated with palmoplantar diversification,etc.,disease contains its progressive symmetry erythema Angle and variability erythema keratinization disease clinical subtypes,two kinds of progressive symmetry erythema keratinization disorder(PSEK),also known as symmetry progressive congenital erythroderma disease,the skin is autosomal dominant genetic disease.This paper reviews the related situation of progressive symmetric erythematosis.

关 键 词：进行性 对称性红斑角化症 遗传 

分 类 号：R394[医药卫生—医学遗传学]