四川泸州地区口腔扁平苔藓致病危险因素分析  

Analysis on the risk factors of oral lichen planus in Luzhou area,Sichuan province

作　　者：郭梦瑶 聂敏海 刘旭倩 GUO Mengyao;NIE Minhai;LIU Xuqian(Department of Periodontics&Oral Mucosal Diseases,The Affiliated Stomatology Hospital of Southwvest Medical University,China,Luzhou646000)

机构地区：[1]西南医科大学附属口腔医院牙周黏膜病科,泸州646000

出　　处：《实用口腔医学杂志》2020年第4期632-636,共5页Journal of Practical Stomatology

基　　金：四川省医学科研课题计划(编号:Q18032);西南医科大学校级科研重点项目(编号:2018-ZRZD-005);四川省科学技术厅科技计划项目(编号:2020YJ0387)。

摘　　要：目的:探究四川泸州地区口腔扁平苔藓(OLP)致病危险因素。方法:纳入至西南医科大学附属口腔医院就诊的OLP患者(病例组,n=171)及同期的口腔黏膜健康者(对照组,n=165)进行22个变量的问卷调查,所得数据行单因素分析后再行Logistic回归分析,筛选出危险因素并进行危险度的排序。结果:单因素分析显示13个变量可能对OLP的发病有影响(P<0.05),Logistic分析显示OLP致病因素按危险度从高至低排列为:失眠、抑郁、性别(女性)、喜食熏烤类食物、焦虑、消化系统疾病、年龄、口内局部刺激。结论:OLP为多因素疾病,其预防措施的制定须从多方面考虑。Objective: To investigate the risk factors of oral lichen planus in Luzhou area,Si Chuan province. Methods: 171 patients with oral lichen planus(case group) and 165 volunteers with normal oral mucosa(control group) were included. The questionnaire survey with 22 variables was conducted. The resulting data were analyzed by Logistic regression analysis after univariate analysis. Risk factors were screened and ranked. Results: The univariate analysis showed that 13 variables may have an effect on the incidence of OLP(P<0.05). The Logistic analysis showed that the risk factors of OLP were ranked from the greatest to the least: Insomnia, depression, gender(female), addiction of smoked food, anxiety, digestive system diseases, age, and local stimulation in the mouth. Conclusion: OLP is a multi-factor disease,and its prevention measures should be considered from many aspects.

关 键 词：口腔扁平苔藓(OLP) 危险因素 LOGISTIC回归分析 

分 类 号：R781.5[医药卫生—口腔医学]