甘氨酸喷砂辅助龈下刮治和根面平整术治疗慢性牙周炎效果及对龈沟液量和白介素-6水平的影响  

The effects of glycine powder air-polishing as an adjuvant for subgingival scaling and root planing in the treatment of periodontitis and its effect on IL-6 level of gingival crevicular fluid

作　　者：胡婷婷 姚佳倩 邹小炎 叶芳[1] HU Tingting;YAO Jiqian;ZU Xiaoyan;YE Fang(Department of Periodontics Afiliated Stomatological Hospital of Nanchang University,Key Laboratory of Oral Biomedicine,Jiangxi Province,China,330006)

机构地区：[1]南昌大学附属口腔医院牙周病科,江西省口腔生物医学重点实验室,330006

出　　处：《实用口腔医学杂志》2020年第4期643-646,共4页Journal of Practical Stomatology

基　　金：江西省自然科学基金(编号:20151BAB205095)。

摘　　要：目的:探讨甘氨酸喷砂辅助慢性牙周炎患者牙周非手术治疗的临床效果及对龈沟液量和IL-6水平的影响。方法:对纳入的31例患者进行左右半口自身对照实验在探诊深度≥4mm的位点随机进行甘氨酸喷砂(实验组)和空气冲洗(对照组)。测量治疗前、后2组患牙的临床探诊深度(PD)、出血指数(BI),龈沟液体积(GCF)和龈沟液中IL-6的浓度。结果:治疗1个月后,2组患者PD、BI、IL-6浓度均下降(P<0.05),组间差异无统计学意义(P>0.05),实验组龈沟液量小于对照组(P<0.05)。结论:甘氨酸喷砂辅助治疗后龈沟液量减少可能有助于牙周炎症状的改善。Objective: To investigate the clinical effects of glycine powder air-polishing an adjuvant for subgingival scaling and root planing(SSRP) in the treatment of chronic periodontitis and its effects on gingival crevicular fluid(GCF) volume and IL-6 level. Methods: 31 patients were randomized to the left and right half of the self-controlled experiment. The teeth with a probing depth(PD) of ≥4 mm were treated by SSRP followed by glycine powder air-polishing(experimental group) and air flush(control group) respectively. The PD, bleeding index(BI), gingival crevicular fluid volume(GCF) and IL-6 concentration in GCF were measured before treatment and 1 month after treatment. Results: After 1 month of treatment, PD, BI, and IL-6 level were decreased in the 2 groups(P<0.05). There was no statistical significance between the 2 groups(P>0.05), but GCF in the experimtal group was less than that in the control group(P<0.05). Conclusion: Inhibition of GCF production by glycine powder air-polishing may contribute to the control of periodontal inflammation.

关 键 词：甘氨酸喷砂 慢性牙周炎 龈下刮治术+根面平整术(SSRP) 龈沟液(GCF) 白介素-6(IL-6) 

分 类 号：R781.4[医药卫生—口腔医学]