平均动脉压对不同程度责任血管狭窄急性进展性缺血性脑卒中的影响  

Effects of mean arterial pressure on acute progressive ischemic stroke with varying degrees of responsible vascular stenosis

作　　者：赵智江[1] 刘芳芳[1] 高凤国[1] 张颖[1] 张二娜 李继业[1] 孔志平 廖仁昊[1] Zhao Zhijing;Liu Fangfang;Gao Fengguo;Zhang Ying;Zhang Erna;Li Jiye;Kong Zhiping;Liao Renhao(Department of Neurology,the First Hospital of Baoding,Baoding 071000,China)

机构地区：[1]保定市第一医院神经内科,河北保定071000

出　　处：《中华脑血管病杂志（电子版）》2020年第3期159-162,共4页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

基　　金：吴阶平医学会基金会临床科研专项资助基金(320.6750.18456)。

摘　　要：目的分析在责任血管不同狭窄程度时,平均动脉压对急性进展性缺血性脑卒中的影响。方法回顾性分析保定市第一医院2017年1月至2018年6月收治的符合标准的急性进展性缺血性脑卒中患者,入院后均给予72 h血压监测。根据责任血管狭窄程度将符合标准的急性进展性缺血性脑卒中患者分为责任血管中度狭窄组及重度狭窄组,通过自身配对的t检验,分别比较不同责任血管狭窄组,进展前后平均动脉压变化的差异。结果中度狭窄组进展前平均动脉压高于进展后平均动脉压[(113.62±10.17)mmHg vs(101.3±12.6)mmHg,1 mmHg=0.133 kPa],差异具有统计学意义(t=3.4648,P=0.026)。重度狭窄组进展前平均动脉压高于进展后平均动脉压,差异无统计学意义(P>0.05)。结论在责任血管中度狭窄的急性缺血性脑卒中患者治疗中,要密切关注血压情况,防止出现低血压导致病情进展。在责任血管重度狭窄的急性缺血性脑卒中患者治疗中,需要适度关注血压情况。Objective The effect of mean arterial pressure on acute progressive ischemic stroke was analyzed for different degrees of stenosis in the responsible vessels.Methods Retrospective analysis was performed on patients with acute progressive ischemic stroke who met the inclusion criteria and were admitted to the First Hospital of Baoding from January 2017 to June 2018.Blood pressure was monitored for 72 hours after admission.According to responsible vascular stenosis degree,patients with acute progressive ischemia stroke were divided into vascular moderate stenosis group and vascular severe stenosis group.The differences of mean arterial pressure before and after the progression of stenosis were compared among the groups with different responsibilities.byt-test of self-pairing Results Mean arterial pressure before progression was higher in the moderate stenosis group than after progression[(113.62±10.17)mmHg vs(101.3±12.6)mmHg],the difference was statistically significant(t=3.4648,P=0.026).The mean arterial pressure before progression in the severe stenosis group was higher than that after progression,and the difference was not statistically significant(P>0.05).Conclusion In the treatment of acute ischemic stroke patients with moderate vascular stenosis,blood pressure should be paid close attention to prevent the occurrence of hypotension leading to disease progression.Appropriate attention should be paid to blood pressure in the treatment of acute ischemic stroke patients with severe vascular stenosis.

关 键 词：缺血性脑卒中 急性 进展性 平均动脉压 责任血管狭窄 

分 类 号：R743.3[医药卫生—神经病学与精神病学]