Gastric neuroendocrine tumor: A practical literature review  

作　　者：Gabriel Antonio Roberto Carolina Magalhães Britto Rodrigues Renata D’Alpino Peixoto Riad Naim Younes 

机构地区：[1]Bachelor Medicine,União das Faculdades dos Grandes Lagos,São Josédo Rio Preto,15030070,Brazil [2]Department of Oncology,Hospital Alemão Oswaldo Cruz,São Paulo 01327001,Brazil [3]Universidade Nove de Julho,São Paulo 01327001,Brazil [4]Department of Thoracic Surgery,Hospital Alemão Oswaldo Cruz,São Paulo 01327001,Brazil

出　　处：《World Journal of Gastrointestinal Oncology》2020年第8期850-856,共7页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group,named gastroenteropancreatic neuroendocrine tumors.They are considered rare and variable in terms of their clinical,morphological and functional characteristics and may be indolent or aggressive.They are classified into types I,II and III,according to their pathophysiology,behavior and treatment.Their diagnosis occurs,in most cases,incidentally during upper digestive endoscopies,presenting as simple gastric polyps.Most cases(type I and type II)are related to hypergastrinemia,can be multiple and are treated by endoscopic resection,whenever possible.The use of somatostatin analogs for tumor control may be one of the options for therapy,in addition to total or subtotal gastrectomy for selected cases.Adjuvant chemotherapy is only reserved for poorly differentiated neuroendocrine carcinomas.Although rare,gastric neuroendocrine tumors have an increasing incidence over the years,therefore deserving more comprehensive studies on its adequate treatment.The present study reviews and updates management recommendations for gastric neuroendocrine tumors.

关 键 词：Gastric neuroendocrine tumor Gastroenteropancreatic tumor HYPERGASTRINEMIA Gastric carcinoid Endoscopic resection 

分 类 号：R735.2[医药卫生—肿瘤]