血管相关因素与帕金森病认知功能障碍的研究进展  

Research progress of vascular factors in Parkinson′s disease with cognitive impairment

作　　者：黄河灵 高玉元[1] 王丽娟[1] Huang Heling;Gao Yuyuan;Wang Lijuan(Department of Neurology,Guangdong Provincial People′s Hospital(Guangdong Neuroscience Institute),Guangzhou 510080,China)

机构地区：[1]广东省人民医院神经科(广东省医学科学院),广州510080

出　　处：《中华神经科杂志》2020年第7期540-543,共4页Chinese Journal of Neurology

基　　金：国家自然科学基金资助项目(81671275,81974195);国家重点研发计划(2017YFC1310200)。

摘　　要：帕金森病是常见的神经系统退行性疾病,认知功能障碍是帕金森病临床常见的非运动症状,可进展至痴呆,严重影响患者的生活质量和寿命。因此正确认识帕金森病认知功能障碍的病因及机制有助于疾病的诊断和治疗。近年来血管因素与帕金森病发生发展的关系成为研究热点,本文对血管相关因素与帕金森病认知功能障碍联系的研究进展做一综述。Parkinson′s disease is a degenerative disease,in which cognitive impairment is main non-motor symptom.It can develop to dementia and seriously affect the quality of life and life expectancy of patients.Therefore,a correct understanding of the etiology and mechanism of cognitive impairment in Parkinson′s disease is helpful for the disease diagnosis and treatment.In recent years,the correlation between vascular factors and the development of Parkinson′s disease has become a research hot topic.This article reviewed the research progress of the correlation between vascular related factors and cognitive impairment in Parkinson′s disease.

关 键 词：帕金森病 认知功能障碍 痴呆 血管因素 

分 类 号：R742.5[医药卫生—神经病学与精神病学]