社交焦虑障碍与认知功能的相关性研究  

Study of the relationship between social anxiety disorder and cognitive function

作　　者：徐彩霞[1] 俞洋[1] 汤超华 徐国洪[1] 张杏莲[1] 邓丹文 谢国军[1] XU Cai-xia;YU Yang;TANG Chao-hua;XU Guo-hong;ZHANG Xing-lian;DENG Dan-wen;XIE Guo-jun(Department of Clinical Psychology,the Third People's Hospital of Foshan City,Foshan 528041,China)

机构地区：[1]广东佛山市第三人民医院临床心理科,528041

出　　处：《临床精神医学杂志》2020年第4期257-259,共3页Journal of Clinical Psychiatry

基　　金：佛山市十三五医学特色专科(FSTSZK002);佛山市医学科技类攻关项目(2018AB002871)。

摘　　要：目的:探讨社交焦虑障碍(SAD)患者的社交障碍与认知功能的关系。方法:对60例SAD患者(SAD组)及60名性别、教育程度和年龄匹配的健康对照者(正常对照组)进行成套神经认知功能[包括威斯康辛卡片分类测验(WCST)、持续操作功能测试(CPT)、踪迹描绘测验(TMT)、词语流畅性测验(WFT)和听觉词语学习测验(AVLT)]评估及比较;并对患者进行利博维茨社交焦虑量表(LSAS)、状态-特质焦虑量表(STAI)及贝克抑郁量表第2版(BDI-II)临床评估;采用皮尔逊相关性对SAD患者临床状况评分与神经心理测试指标进行相关性分析。结果:SAD组WCST测试的完成分类数的测试分(5.2±1.4)明显低于正常对照组(5.3±0.6),持续性错误数(1.6±2.7)明显高于正常对照组(0.7±0.7)(P均<0.05);LSAS评分(63.5±25.5)明显高于正常值(28.4±21.5);SAD组LSAS评分与WCST的持续性错误数呈正相关(r=0.535,P<0.05),与WCST分类成绩呈负相关(r=-0.353,P<0.05)。结论:SAD患者认知功能中的执行能力明显降低,并与SAD严重程度相关。Objective:To investigate the correlation between social disorder and cognitive function in patients with social anxiety disorders(SAD).Method:60 SAD patients(SAD group)and 60 gender-,education-and age-matched healthy subjects(control group)were enrolled in the study.Both of the two groups were assessed by neuropsychological and clinical methods.The neuropsychological assessments included Wisconsin card sorting test(WCST),the continuous performance test(CPT),the trail-making test(TMT),the word fluency test(WFT)and the auditory verbal learning test(AVLT).The clinical assessments include Liebowitz social anxiety scale score(LSAS)and Beck depression inventory-decond edition score(BDI-II).The correlation between the neuropsychological and clinical methods were also analyzed.Results:The WCST categories completed of SAD group(5.2±1.4)were significantly lower than those of the control group(5.3±0.6)(P<0.05).However the WCST perseverative errors of SAD group(1.6±2.7)were significantly higher compared to the control group(0.7±0.7)(P<0.05).LSAS(63.5±25.5)was significantly higher than the norm(28.4±21.5).LSAS showed significantly positive correlation with perseverative errors in WCST(r=0.535,P<0.05)and significantly negative correlation with the WCST categories completed(r=-0.353,P<0.05).Conclusion:The cognitive function of patients with SAD is significantly low,mainly in executive function and the lower executive function correlates with the severity of social anxiety disorder.

关 键 词：社交焦虑障碍 认知功能 神经心理学评估 

分 类 号：R749.7[医药卫生—神经病学与精神病学]