甲状腺全切术对分化型甲状腺癌患者PTH、血钙水平的影响  

The effect of total thyroidectomy on the level of PTH and blood calcium in differentiated thyroid carcinoma

作　　者：王伟 Wang Wei(Zaozhuang Mining Group,Tengnan Hospital,Zaozhuang,Shandong,277000,China)

机构地区：[1]枣庄矿业集团滕南医院普通外科,山东枣庄277000

出　　处：《当代医学》2020年第23期35-37,共3页Contemporary Medicine

摘　　要：目的探讨甲状腺全切术治疗分化型甲状腺癌患者的临床效果。方法回顾分析2017年5月至2018年10月本院收治80例分化型甲状腺癌患者的临床资料,依据治疗方式不同分为对照组(甲状腺次全切除,n=40)与观察组(甲状腺全切术,n=40)。对比两组患者临床相关指标与复发率,同时比较两组患者术前与术后甲状旁腺激素(PTH)与血钙水平变化。结果两组患者手术时间、术中出血量、住院时间对比差异无统计学意义;术前,两组患者PTH、血钙水平对比差异无统计学意义;术后1 d与术后2 d,两组患者PTH、血钙水平均低于术前,且观察组患者PTH、血钙水平均低于对照组,差异有统计学意义(P<0.05);与对照组比较,观察组患者复发率较低,差异有统计学意义(P<0.05)。结论甲状腺全切术治疗分化型甲状腺癌患者在一定程度上能降低患者PTH与血钙水平,但不影响患者术后身体恢复,且术后复发率较低。Objective To investigate the clinical effect of total thyroidectomy in the treatment of differentiated thyroid carcinoma. Methods The clinical data of 80 cases of differentiated thyroid carcinoma in our hospital from May 2017 to October 2018 were retrospectively analyzed. According to different treatment methods, they were divided into control group(subtotal thyroidectomy, n=40) and observation group(total thyroidectomy, n=40). The clinical-related indexes and the recurrence rate of the two groups were compared, and compare the changes of the parathyroid hormone(PTH) and the level of blood calcium were compared between the two groups before and after operation. Results There was no significant difference in operative time of the two groups, the amount of intraoperative blood loss, the time of hospitalization between the two groups. Before operation, there was no significant difference in PTH, blood calcium level between the two groups, 1 day and 2 days after operation, the blood calcium level of the two groups was lower than before operation, the observation group patients with PTH, blood calcium level were lower than the control group patients, and the difference was statistically significant(P<0.05). Compared with the control group, the recurrence rate of the observation group was lower, and the difference was statistically significant(P<0.05). Conclusion Total thyroidectomy can decrease PTH and serum calcium in patients with differentiated thyroid carcinoma, but it does not affect the patient’ s postoperative physical recovery, and the postoperative recurrence rate is low.

关 键 词：分化型甲状腺癌 甲状腺全切术 甲状腺次全切术 甲状旁腺激素 血钙 

分 类 号：R736.1[医药卫生—肿瘤]