新型合成大麻素5F-MDMB-PICA的波谱特征及结构确证  

The spectral characteristics and structural confirmation of a new synthetic cannabinoid 5F-MDMB-PICA

作　　者：曾静 蔡玉刚 杨沁之 张开莲 ZENG Jing;CAI Yugang;YANG Qinzhi;ZHANG Kailian(School of Pharmacy,Southwest Medical University,Luzhou 646000;Institute of Criminal Science and Technology,Luzhou Public Security Bureau,Luzhou 646000)

机构地区：[1]西南医科大学药学院,泸州646000 [2]泸州市公安局刑事科学技术研究所,泸州646000

出　　处：《分析试验室》2020年第7期854-859,共6页Chinese Journal of Analysis Laboratory

基　　金：西南医科大学人才引进项目(0903-0040029)资助。

摘　　要：采用硅胶层析法纯化合成大麻素目标成分,利用紫外光谱、红外光谱、高分辨质谱和核磁共振法研究其波谱学特征以确定结构。结果表明,目标成分为一种暂未列入管制目录的具有吲哚母核的新型合成大麻素衍生物5F-MDMB-PICA,是一种国内首次发现并报道的新型高活性合成大麻素。本文提供了更为准确、全面的紫外、红外、高分辨质谱和核磁谱等波谱学数据,可供相关单位参考。Silica gel chromatography was used to purify the component of synthetic cannabinoids.Ultraviolet spectrum(UV),infrared spectroscopy(IR),high resolution mass spectrometry(HRMS)and nuclear magnetic resonance(NMR)were used to identify the structure.The results indicated that the compound was a new synthetic cannabinoid with indoles nucleus named 5F-MDMB-PICA,which was a new psychoactive substance reported in China for the first time.Compared with the literature,more accurate data of UV,IR,HRMS,NMR were reported,which provides a valuable references for the drug agency.

关 键 词：合成大麻素 5F-MDMB-PICA 波谱特征 结构确证 

分 类 号：O656.4[理学—分析化学]