脑脉泰胶囊联合阿托伐他汀钙治疗皮质下缺血性脑血管病的疗效观察  

Observation on the Efficacy of Naomaitai Capsule Combined with Atorvastatin Calcium in the Treatment of Subcortical Ischemic Cerebrovascular Disease

作　　者：冯瑞雪[1] FENG Rui-xue(The Second Department of Neurology,Jiamusi Central Hospital,Jiamusi,Heilongjiang,154002,China)

机构地区：[1]佳木斯市中心医院神经内二科,黑龙江佳木斯154002

出　　处：《黑龙江医学》2020年第8期1087-1089,共3页Heilongjiang Medical Journal

摘　　要：目的探讨脑脉泰胶囊联合阿托伐他汀钙治疗皮质下缺血性脑血管病的疗效。方法选取佳木斯市中心医院2018年10月—2019年10月期间收治的皮质下缺血性脑血管病患者70例,采用随机数字表法分为两组,每组各35例。对照组给予常规治疗+脑脉泰胶囊治疗,观察组给予常规治疗+脑脉泰胶囊联合阿托伐他汀钙治疗,比较两组颈部血管斑块情况、神经功能损伤程度、日常生活活动能力。结果治疗前,两组颈部斑块的情况(厚度、面积、长度)比较,差异无统计学意义(P>0.05);治疗后,观察组颈部血管斑块的厚度、长度、面积均低于对照组,差异有统计学意义(P<0.05);治疗前,两组美国国立卫生研究院卒中量表(NIHSS)、Barthel指数(BI指数)比较,差异无统计学意义(P>0.05),治疗后,观察组患者的NIHSS评分小于对照组患者,BI评分大于对照组患者,差异有统计学意义(P<0.05)。结论皮质下缺血性脑血管病患者给予脑脉泰胶囊联合阿托伐他汀钙治疗的效果较好,可以有效缩小患者颈部血管斑块,减轻神经功能缺损程度,改善其日常生活活动能力,提高生活质量。Objective To investigate the efficacy of Naomaitai capsule combined with atorvastatin calcium in the treatment of subcortical ischemic cerebrovascular disease. Methods 70 patients with subcortical ischemic cerebrovascular disease treated in the hospital from October, 2018 to October, 2019 were selected, and divided into two groups by random number table method, with 35 patients in each group. The control group was given conventional treatment + Naomaitai capsule treatment, and the observation group was given conventional treatment + Naomaitai capsule combined with atorvastatin calcium treatment. The condition of cervical vascular plaque, the degree of nerve function damage, and the ability of daily living were compared between the two groups. Results Before treatment, there was no significant difference in the condition(thickness, area and length) of cervical plaque between the two groups(P>0.05). After treatment, the thickness, length and area of cervical plaque in the observation group were low. The difference was statistically significant(P<0.05). Before treatment, the scores of National Institutes of Health Stroke Scale(NIHSS)and Barthel Index(BI Index) were compared, and the difference was not statistically significant(P>0.05). After treatment, patients in the observation group had lower NIHSS scores than those in the control group, and BI scores were greater than those in the control group. The difference was statistically significant(P<0.05). Conclusion Patients with subcortical ischemic cerebrovascular disease are better treated with Naomaitai capsule combined with atorvastatin calcium, which can effectively reduce the neck vascular plaques and the degree of neurological deficits, and improve their daily activities and the quality of life.

关 键 词：皮质下缺血性脑血管病 脑脉泰胶囊 阿托伐他汀钙 神经功能 日常生活活动能力 

分 类 号：R743[医药卫生—神经病学与精神病学]