影像组学在局部进展期直肠癌新辅助放化疗中的预测价值  

The value of radiomics for prediction of treatment response to neoadjuvant chemoradiotherapy for locally advanced rectal cancer

作　　者：李峥艳[1] 汪晓东[2] 黄子星[1] 宋彬[1] LI Zhengyan;WANG Xiaodong;HUANG Zixing;SONG Bin(Department of Radiology,West China Hospital,Sichuan University,Chengdu 610041,P.R.China;Department of Gastrointestinal Surgery,West China Hospital,Sichuan University,Chengdu 610041,P.R.China)

机构地区：[1]四川大学华西医院放射科,成都610041 [2]四川大学华西医院胃肠外科,成都610041

出　　处：《中国普外基础与临床杂志》2020年第8期1016-1022,共7页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的总结影像组学(radiomics)对局部进展期直肠癌(locally advanced rectal cancer,LARC)新辅助放化疗(neoadjuvant chemoradiotherapy,NCRT)疗效的预测价值。方法通过查阅总结相关文献,对影像组学的研究方法及其在LARC行NCRT的疗效评价方面的预测价值进行总结。结果在NCRT后是否达到病理完全缓解(pathologic complete response,pCR)、治疗有效或无效方面,影像组学均具有良好的预测价值。结论影像组学是一项新兴的影像学诊断技术,在LARC行NCRT疗效的预测中发挥着重要作用。Objective To make a comprehensive review of the value of radiomics for prediction of therapeutic responses to neoadjuvant chemoradiotherapy(NCRT)in patients with locally advanced rectal cancer(LARC).Method Relevant literatures about the therapeutic response evaluation of LARC by using radiomics were collected to make an review.Result Radiomics had good predictive value in terms of complete pathologic response(pCR)and treatment effectiveness of NCRT in patients with LARC.Conclusion Radiomics,a new imaging diagnostic technique,plays an important role in the prediction of the efficacy of NCRT in LARC.

关 键 词：局部进展期直肠癌 新辅助治疗 影像组学 综述 

分 类 号：R735.37[医药卫生—肿瘤]