原发性空蝶鞍筛查及30例临床分析  

Screening and clinical analysis of primary empty sella: A report of 30 cases

作　　者：王伟军 史峰 王芳 任斌 Wang Weijun;Shi Feng;Wang Fang;Ren Bin(Department of air crew surgery,Shanghai Hospital of Civil Aviation,Shanghai 200336,China)

机构地区：[1]民航上海医院空勤外科,200336

出　　处：《中国微侵袭神经外科杂志》2020年第5期209-211,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨原发性空蝶鞍的患病率及临床特点。方法选取40岁及以上健康男性2710人行头颅MRI检查,对空蝶鞍者行垂体激素水平检查和视野检查。结果 MRI发现原发性空蝶鞍30例,检出率为1.1%;其中完全性空蝶鞍13例,部分性空蝶鞍17例。年龄40~60岁,平均(44.2±6.1)岁,以40~45岁最多见。所有检出者无临床症状,垂体激素水平及视野检查均在正常范围。30例原发性空蝶鞍平均随访(42±16)个月,均未见明显异常改变。结论原发性空蝶鞍多无症状,无需临床治疗,给予定期随访。Objective To analyze the prevalence rate and clinical characteristics of primary empty sella. Methods A total of 2710 healthy males aged 40 and above were selected for cranial MRI examination, then, the level of pituitary hormone and visual field were assessed in patients with primary empty sella(PES). Result PES was found in 30 patients with a detection rate of 1.1%, including complete empty sella in 13 patients and partial empty sella in 17. The average age was 44.2 ± 6.1 years, ranging from 40 to 60 years,and the most patients were between 40 to 45 years. No clinical symptoms occurred in all the patients, and the level of pituitary hormone and visual field were in the normal range. Thirty PES patients were followed up for mean time of 42 ± 16 months, and no obviously abnormal change was observed. Conclusion Most PES patients are asymptomatic, requiring no clinical treatment except regular follow-up.

关 键 词：空蝶鞍 原发性 患病率 磁共振 筛查 

分 类 号：R742.8[医药卫生—神经病学与精神病学]