蓝激光放大胃镜对胃黏膜萎缩及肠上皮化生的诊断价值  

Diagnostic Value of Blue Laser Magnifying Gastroscope for Gastric Mucosal Atrophy and Intestinal Metaplasia

作　　者：赖辉[1] 余焰 钟福杭 LAI Hui;YU Yan;ZHONG Fu-hang(Department of Gastroenterology,Shanghang County Hospital,Longyan 364200,Fujian,China;Department of Pathology,Shanghang County Hospital,Longyan 364200,Fujian,China)

机构地区：[1]上杭县医院消化内科,福建龙岩364200 [2]上杭县医院病理科,福建龙岩364200

出　　处：《医学信息》2020年第15期167-169,共3页Journal of Medical Information

摘　　要：目的探讨蓝激光放大胃镜对胃粘膜萎缩及肠上皮化生的诊断效果。方法选取2019年5月~2020年4月我院门诊及住院收治的上消化道症状患者113例作为研究对象,所有患者行无痛蓝激光胃镜检查。根据不同观察模式下胃粘膜肠上皮化生特异性表现进行分组:联动成像(LCI)模式下见淡紫色调,蓝激光放大胃镜(BLI-ME)下未见亮蓝嵴的患者纳入α组;LCI模式下未见淡紫色调、BLI-ME模式下存在亮蓝嵴的患者纳入β组;LCI模式下见淡紫色调且BLI-ME模式存在亮蓝嵴的患者纳入γ组。比较三组HP、活动性、炎性、萎缩及肠化生发生情况;结合病理诊断结果与内镜诊断结果,比较三组肠化生诊断的灵敏度、特异性、准确性。结果三组HP、活动性、炎性及萎缩患者比较,差异无统计学意义(P>0.05);三组患者肠化生例数比较,差异有统计学意义(P<0.05);γ组胃粘膜肠上皮化生诊断的敏感性、特异性及准确性均高于α、β组,α组的敏感性、特异性及准确性略高于β,差异有统计学意义(P<0.05)。对蓝激光胃镜下胃黏膜萎缩的白光、LCI、BLI-bri及BLI-ME镜下及病理表现予以观察,LCI及BLI观察模式下胃黏膜萎缩表现较白光下敏感性、特异性及准确性均较高。结论蓝激光放大胃镜对于胃粘膜萎缩及肠上皮化生具有较高的诊断价值,LCI及BLI观察模式下胃黏膜萎缩表现较白光下敏感性、特异性及准确性均较高。Objective To investigate the diagnostic effect of blue laser magnifying gastroscope on gastric mucosal atrophy and intestinal metaplasia.Methods 113 patients with upper gastrointestinal symptoms admitted to our hospital from May 2019 to April 2020 were selected as the research objects.All patients underwent painless blue laser gastroscopy.Groups were grouped according to the specific manifestations of gastric mucosal intestinal metaplasia under different observation modes:patients with lavender hue under Linked Imaging(LCI)mode and no bright blue ridge under blue laser magnifying gastroscope(BLI-ME)were included in theαgroup;Patients with no lavender tone in LCI mode and bright blue ridge in BLI-ME mode were included in theβgroup;patients with lavender tone in LCI mode and bright blue ridge in BLI-ME mode were included in theγgroup.Compare the occurrence of HP,activity,inflammation,atrophy and intestinal metaplasia in the three groups;combine the results of pathological diagnosis and endoscopic diagnosis to compare the sensitivity,specificity and accuracy of the diagnosis of intestinal metaplasia in the three groups.Results There was no statistically significant difference among the three groups of patients with HP,activity,inflammation and atrophy(P>0.05);the three groups of patients with intestinal metaplasia compared with the number of cases,the difference was statistically significant(P<0.05);the stomach of theγgroup the sensitivity,specificity and accuracy of the diagnosis of mucosal intestinal metaplasia were higher than those of theαandβgroups.The sensitivity,specificity and accuracy of theαgroup were slightly higher than that ofβ,the difference was statistically significant(P<0.05).The white light,LCI,BLI-bri and BLI-ME microscopic and pathological manifestations of gastric mucosal atrophy under blue laser gastroscopy were observed.The sensitivity,specificity and accuracy of gastric mucosal atrophy under LCI and BLI observation modes are higher than those under white light.Conclusion Blue laser ma

关 键 词：蓝激光放大胃镜 胃粘膜萎缩 肠上皮化生 

分 类 号：R573[医药卫生—消化系统]