多普勒超声对甲状腺癌患者血流动力学指标评估及与淋巴结转移的相关性分析  

Evaluation of hemodynamic index and its correlation with lymph node metastasis in patients with thyroid cancer by doppler ultrasound.

作　　者：魏亚丽 陈国萍[1] 曾浪 唐梅 杨欣 WEI Ya-li;CHEN Guo-ping;ZENG Lang(Department of Color Doppler Ultrasound;Department of Otolaryngology Head and Neck Surgery,Guang'an People's Hospital,Guang'an Sichuan 638000,China.)

机构地区：[1]广安市人民医院彩超科,四川广安638000 [2]广安市人民医院耳鼻喉头颈外科,四川广安638000

出　　处：《临床和实验医学杂志》2020年第16期1779-1782,共4页Journal of Clinical and Experimental Medicine

基　　金：四川省卫生厅科研课题(编号:120286)。

摘　　要：目的分析多普勒超声对甲状腺癌患者血流动力学指标的评估及与淋巴结转移的相关性。方法本研究为回顾性研究,选取2016年9月至2019年6月广安市人民医院收治的52例甲状腺癌患者作为甲状腺癌组,其中32例有淋巴结转移,20例无淋巴结转移;同时选取同期收治的56例甲状腺良性疾病患者作为对照组,所有患者均接受多普勒超声检查,对比对照组与甲状腺癌组、甲状腺病灶不同血流分级组、甲状腺癌有无淋巴结转移组的血流动力学参数及甲状腺癌有无淋巴结转移组的淋巴结超声声像图表现。结果对照组和甲状腺癌组患者的健侧血流动力学参数比较,差异无统计学意义(P>0.05);甲状腺癌组患者患侧收缩期流速(S)、舒张期流速(D)值分别为(48.08±6.94)cm/s、(29.11±3.77)cm/s,均高于对照组,阻力指数(RI)、搏动指数(PI)值分别为0.83±0.10、0.53±0.06,均低于对照组,差异具有统计学意义(P<0.05)。甲状腺癌血流分级Ⅰ级组S、D低于Ⅱ级及Ⅲ级组,RI、PI高于Ⅱ级及Ⅲ级组,差异具有统计学意义(P<0.05)。甲状腺癌患者有淋巴结转移组RI、收缩期峰值流速(PSV)分别为0.88±0.11、(27.61±3.29)cm/s,均高于无淋巴结转移组,差异具有统计学意义(P<0.05)。甲状腺癌患者有淋巴结转移组纵横比(L/S)<2、内部回声不均、边界不清、微钙化、血流丰富、信号杂乱率分别为65.63%、68.75%、62.50%、59.38%、84.38%、59.38%,均显著高于无淋巴结转移组,差异具有统计学意义(P<0.05)。结论多普勒超声测定甲状腺患者的相关血流动力学参数,能够为甲状腺癌的诊断及淋巴结转移的判断提供参考依据。Objective To analyze the correlation between Doppler ultrasound and lymph node metastasis according to evaluating hemodynamic indexes of thyroid cancer patients.Methods This study was a retrospective study.The clinical data of 52 patients with thyroid cancer treated in Guang'an People's Hospital from September 2016 to June 2019 were selected,including 32 patients with lymph node metastasis and 20 patients without lymph node metastasis.At the same time,56 patients with benign thyroid diseases admitted in the same period were selected as control group.All patients were examined by Doppler ultrasound,and the hemodynamic parameters and ultrasonic imaging manifestations of metastatic lymph nodes in each group were compared.Results There was no statistical difference between the healthy side hemodynamic parameters of the control group and the thyroid cancer group(P>0.05).In thyroid cancer group,systolic velocity(S)and diastolic velocity(D)was(48.08±6.94)cm/s and(29.11±3.77)cm/s respectively,which was higher than those in control group.Resistance index(RI)and pulsatility index(PI)were 0.83±0.10 and 0.53±0.06 respectively,which was lower than those in control group(P<0.05).The blood flow classification of thyroid cancer group I was lower in S and D than that of group II and III,and higher in RI and PI than that of group II and III,there was a statistical difference(P<0.05).RI and peak systolic velocity(PSV)in patients with thyroid cancer with lymph node metastasis were 0.88±0.11 and 27.61±3.29 cm/s respectively,which was higher than those without lymph node metastasis(P<0.05).In thyroid cancer patients with lymph node metastasis group,the latitude ratio(L/S)<2,the internal echo was uneven,the boundary was unclear,the microcalcification,the flow was abundant,and the signal clutter rate was 65.63%,68.75%,62.50%,59.38%,84.38%and 59.38%respectively,which was higher than that of the group without lymph node metastasis,there was a statistical difference(P<0.05).Conclusion Doppler ultrasound determination of the relevant

关 键 词：甲状腺癌 多普勒超声 血流动力学 淋巴结转移 

分 类 号：R736.1[医药卫生—肿瘤]