吲哚菁绿荧光融合影像技术在完全腹腔镜右半结肠癌根治术中的应用价值  

Application value of indocine green fluorescence fusion imaging technique in complete laparoscopic radical resection of right hemicolon carcinoma

作　　者：吴国聪[1] 姚宏伟[1] 郭策 WU Guo-cong;YAO Hong-wei;GUO Ce(Department of General Surgery,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院普通外科,北京100050

出　　处：《临床和实验医学杂志》2020年第15期1626-1628,共3页Journal of Clinical and Experimental Medicine

基　　金：首都医科大学结直肠肿瘤临床诊疗与研究中心(编号:1192070313);国家科技支撑计划课题(编号:2015BAI13B09);国家重点研发计划资助(编号:2017YFC0110904)。

摘　　要：目的探讨吲哚菁绿荧光融合影像技术在完全腹腔镜右半结肠癌根治术中的应用价值。方法回顾性选取2018年2月至2019年2月在首都医科大学附属北京友谊医院行完全腹腔镜右半结肠癌根治术的患者28例,术中采用吲哚菁绿荧光融合影像技术,观察患者的吻合口血供,并观察手术时间、术中出血量、排气时间、住院时间以及肿瘤长径、淋巴结检出数目、病理分期等指标以及患者的并发症发生情况。结果手术时间为110~180 min,平均(132.5±25.4) min;术中出血量为25~125 ml,平均(35.3±5.2) ml。5例(17.86%)患者标本经自然腔道取出,23例(82.14%)患者经耻骨上横切口取出。患者术后排气时间为12~53 h,平均(32.1±10.7) h;住院时间为3~8 d,平均(4.5±1.2)d。肿瘤长径为2.9~7.1 cm,平均(4.6±1.3) cm;淋巴结检出数目为12~57枚,平均(30.5±12.2)枚。肿瘤分期为Ⅰ期的患者5例(17.84%),Ⅱ期患者12例(42.86%),Ⅲ期患者11例(39.29%)。所有患者均未出现吲哚菁绿注射过敏、吻合口狭窄、吻合口漏、肠梗阻、腹腔感染等并发症。结论吲哚菁绿荧光融合影像是一项具有较高安全性的术中应用技术,在完全腹腔镜右半结肠癌根治术中具有较好的应用价值。Objective To investigate the application value of indocyanine green fluorescence fusion imaging technique in complete laparoscopic radical resection of right hemicolon carcinoma.Methods From February 2018 to February 2019,28 patients of colon cancer patients in Beijing Friendship Hospital,Capital Medical University who were treated by half right colon laparoscopic therapy were retrospectively selected.Intraoperative indocyanine green fluorescence image fusion technology was used and patient’s operation time,intraoperative blood loss,exhaust time,length of hospital stay,and number of tumor size,lymph node detection and pathological staging index,occurrence of complications were observed.Results The operative time ranged from 110 to 180 min,with an average operative time of(132.5 ± 25.4) min.The intraoperative blood loss ranged from 25 to 125 ml,with an average intraoperative blood loss of(35.3 ± 5.2) ml.Specimens were removed from 5(17.86%)patients by natural lumen and 23(82.14%) patients by suprapubic transverse incision.The postoperative exhaust time was 12 ~ 53 h,and the average exhaust time was(32.1 ± 10.7) h.The length of hospital stay ranged from 3 to 8 days,with an average length of hospital stay of(4.5 ±1.2) d.The tumor length ranged from 2.9 to 7.1 cm,with an average tumor length of(4.6 ± 1.3) cm.The number of detected lymph nodes was12 ~ 57,and the average number of detected lymph nodes was(30.5 ± 12.2).5 patients was in Ⅰ stage(17.84%),12 patients in Ⅱ stage(42.86%) and 11 patients in Ⅲ stage(39.29%).All patients had no indocine green injection allergy,anastomotic stenosis,anastomotic leakage,intestinal obstruction,abdominal infection and other complications.Conclusion Indocinine green fluorescence fusion imaging is a safe intraoperative technique,and has a good value in laparoscopic radical resection of right hemicolon carcinoma.

关 键 词：结肠癌 腹腔镜根治术 吲哚菁绿 影像技术 

分 类 号：R735.35[医药卫生—肿瘤]