手性1,2-氨基醇合成进展  

Progress of Synthesis of Chiral 1,2-Amino Alcohol

作　　者：季少天 JI Shao-tian(School of Chemistry and Material engineering,Wenzhou University,Wenzhou Zhejiang 325035,China)

机构地区：[1]温州大学化学与材料工程学院,浙江温州325035

出　　处：《辽宁化工》2020年第7期874-878,共5页Liaoning Chemical Industry

摘　　要：手性1, 2-氨基醇作为合成砌块常被作为起始原料用于生物活性化合物或手性配体的制备,也可以作为手性辅基被直接用于不对称合成。本文简述了手性氨基醇的主要合成方法,并对近些年合成方法的进展予以整理报道。Chiral 1,2-amino alcohols is not only the important synthon in the synthesis of bioactive compounds and chiral ligands,but also chiral cogroups for asymmetric synthesis. In this paper, the main synthetic methods of chiral amino alcohols were described,and the progress of new methods in recent years was discussed.

关 键 词：氨基醇 手性配体 不对称催化 

分 类 号：TQ201[化学工程—有机化工]