HIV/AIDS患者死亡原因和危险因素分析  

Analysis to causes of death and risk factors in HIV/AIDS patients

作　　者：王启明 许娇 尚鹏程 WANG Qiming;XU Jiao;SHANG Pengcheng(Chengdu Public Health Clinical Medical Center,Chengdu,Sichuan 610000,China)

机构地区：[1]成都市公共卫生临床医疗中心,四川成都610000

出　　处：《现代医药卫生》2020年第16期2521-2523,共3页Journal of Modern Medicine & Health

基　　金：四川省成都市科技局课题项目(2018JY0383)。

摘　　要：目的分析成都地区人类免疫缺陷病毒(HIV)/获得性免疫缺乏综合征(AIDS)患者死亡原因和危险因素。方法选取2018年在成都公共卫生临床医疗中心住院治疗的HIV/AIDS患者126例作为研究对象,按照AIDS相关和非AIDS相关进行死亡原因分类,建立COX比例风险模型来分析HIV/AIDS患者死亡危险因素。结果AIDS相关感染是HIV/AIDS患者的重要死亡因素,CD4+T细胞小于或等于100 cell/μL和未接受高效抗逆转录病毒治疗(HAART)这2个风险因素对导致患者死亡具有显著影响。结论积极开展HAART治疗和提高HIV/AIDS患者CD4+T淋巴细胞水平对于改善患者结局具有积极意义。Objective To analyze the causes and risk factors of human immunodeficiency virus(HIV)/acquired immunodeficiency syndrome(AIDS)patients in Chengdu.Methods 126 HIV/AIDS patients hospitalized in the Chengdu Public Health Clinical Medical Center in 2018 were selected as the research object.The causes of death of patients were classified according to AIDS-related and non-AIDS-related.A COX proportional risk model to analyze the risk factors of death in HIV/AIDS patients was established.Results AIDS-related infections were important death factors for HIV/AIDS patients.Two risk factors,CD4+T cells≤100 cell/μL and failure to receive HAART,had significant impacts on the death of patients.Conclusion Actively carrying out HAART treatment and increasing the level of CD4+T lymphocytes in HIV/AIDS patients have a positive significance for improving patient outcomes.

关 键 词：人体免疫缺损病毒 获得性免疫缺陷综合征 感染 死亡原因 CD4+T细胞 高效抗逆转录病毒治疗 

分 类 号：R446[医药卫生—诊断学]