吉西他滨联合奥沙利铂治疗胰腺癌的效果  

Effects of Gemcitabine Combined With Oxaliplatin in the Treatment of Pancreatic Cancer

作　　者：李锐[1] 祝喜萍[1] 李强[1] 穆丽雅[1] 于丹[1] LI Rui;ZHU Xiping;LI Qiang;MU Liya;YU Dan(The Third Department of Gastroenterology,Heilongjiang Provincial Hospital,Harbin Heilongjiang 150000,China)

机构地区：[1]黑龙江省医院消化三科,黑龙江哈尔滨150000

出　　处：《中国卫生标准管理》2020年第15期92-94,共3页China Health Standard Management

摘　　要：目的研究吉西他滨联合奥沙利铂治疗胰腺癌的临床效果。方法入组80例胰腺癌患者,均为本院2019年1月—2019年12月收治入院。以盲选法分为对比组和研究组,各40例。对比组给予吉西他滨治疗,研究组联合奥沙利铂治疗。观察两组疗效和安全性。结果治疗效果对比,研究组总有效率(95.00%)高于对比组(80.00%)(P <0.05)。用药后,研究组不良反应发生率(7.50%)低于对比组(25.00%)(P<0.05)。研究组患者临床受益率高于对比组(P <0.05)。结论将吉西他滨联合奥沙利铂用于胰腺癌的治疗中,效果显著,毒副作用小。Objective To study the clinical effect of gemcitabine combined with oxaliplatin in the treatment of pancreatic cancer.Methods 80 patients with pancreatic cancer were admitted from January 2019 to December 2019.Blind selection method was used to divide them into control group and research group,40 cases each.The control group was treated with gemcitabine and the study group with oxaliplatin.The efficacy and safety of the two groups were observed.Results The total effective rate of the study group(95.00%)was higher than that of the control group(80.00%)(P<0.05).The incidence of adverse reactions in the study group(7.50%)was lower than that in the control group(25.00%)(P<0.05).The clinical benefit rate of the study group was higher than that of the control group(P<0.05).Conclusion Gemcitabine combined with oxaliplatin is effective in the treatment of pancreatic cancer with little toxic and side effects.

关 键 词：胰腺癌 吉西他滨 奥沙利铂 联合治疗 安全性 有效率 

分 类 号：R576[医药卫生—消化系统]