经肝动脉栓塞术治疗不同血供特点的肝血管瘤患者的疗效分析  

Efficacy Analysis of Transcatheter Arterial Embolization for Hepatic Hemangioma Patients with Different Blood Supply Characteristics

作　　者：王儒发 林成 岑炳奎[1] WANG Rufa;LIN Cheng;CEN Bingkui(Baise People's Hospital,Baise,533000)

机构地区：[1]百色市人民医院,533000 [2]右江民族医学院附属医院,533000

出　　处：《实用癌症杂志》2020年第8期1331-1334,共4页The Practical Journal of Cancer

摘　　要：目的探讨经肝动脉栓塞术治疗不同血供特点的肝血管瘤(HL)患者的疗效。方法206例HL患者,根据血供特点将所有患者分为3组,富血供型组、中等血供型组及乏血供型组,所有患者均给予经肝动脉栓塞术进行治疗,栓塞剂为平阳霉素碘油乳剂(PLE)。统计所有患者的血供类型分布,观察并比较3组的PLE用量、瘤体缩小率、瘤体直径及临床疗效。结果206例患者中,中等血供型组最多,最少的是乏血供型组。富血供型组、中等血供型组、乏血供型组的PLE用量分别为(11.4±1.5)ml、(9.7±1.0)ml,(5.1±0.7)ml;瘤体缩小率分别为(64.1±5.9)%,(48.3±4.2)%,(36.9±3.3)%;富血供型组PLE用量及瘤体缩小率最多,乏血供型组PLE用量及瘤体缩小率最少。术前,富血供型组的瘤体直径显著高于乏血供型组的瘤体直径(P<0.05);术后6个月,富血供型组的瘤体直径显著低于中等血供型组、乏血供型组(P<0.05)。乏血供型的显效率和有效率显著低于富血供型组、中等血供型组(P<0.05)。结论采用PLE经肝动脉栓塞介入治疗对富血供型HL患者的疗效较好,可显著改善其瘤体大小,而对乏血供型HL患者的疗效最差,该疗法对富血供型HL患者的临床价值较高。Objective To explore the therapeutic effect of transcatheter arterial embolization for hepatic hemangioma(HL)patients with different blood supply characteristics.Methods 206 HL patients were divided into rich blood supply group,medium blood supply group and poor blood supply group according to blood supply characteristics.All patients were treated by transcatheter arterial embolization with pingyangmycin lipiodol emulsion(PLE).The distribution of blood supply types of all patients were recorded,and the PLE dosage,tumor shrinkage rate,tumor diameter and clinical efficacy of the three groups were compared among the 3 groups.Results Among the 206 patients,the middle blood supply group was the most,and the least was the lack of blood supply group.The dose of PLE was(11.4±1.5)ml,(9.7±1.0)ml,(5.1±0.7)ml in the rich blood supply group,the middle blood supply group and the lack blood supply group,respectively;the tumor reduction rate was(64.1±5.9)%,(48.3±4.2)%,(36.9±3.3)%;the dose of PLE and the tumor reduction rate were the most in the rich blood supply group and the least in the lack blood supply group.Before operation,the tumor diameter of the rich blood supply group was significantly higher than that of the lack blood supply group(P<0.05);after 6 months,the tumor diameter of the rich blood supply group was significantly lower than that of the middle blood supply group and the lack of blood supply group(P<0.05).The significant and effective rates of the poor blood supply group were significantly lower than those of the rich blood supply group and the medium blood supply group(P<0.05).Conclusion PLE transcatheter arterial embolization has better therapeutic effects on HL patients with rich blood supply type,and can significantly improve the tumor size,while it has the worst therapeutic effect on HL patients with poor blood supply type.The therapy has higher clinical value on HL patients with rich blood supply type.

关 键 词：经肝动脉栓塞术 肝血管瘤 疗效 不同血供 瘤体直径 平阳霉素碘油乳剂 

分 类 号：R735.7[医药卫生—肿瘤]