计算机认知矫正治疗对慢性精神分裂症患者社会功能的影响  

Effect of computerized cognitive remediation therapy on social function of patients with chronic schizophrenia

作　　者：程诚 班春霞[1] 沈红艳[1] 徐郁 戴悦宁 王毅[1] CHENG Cheng;BAN Chunxia;SHEN Hongyan(Mental Health Center of Jiading,District in Shanghai,Shanghai 201806,China)

机构地区：[1]中国·上海市嘉定区精神卫生中心,201806 [2]上海市静安区精神卫生中心 [3]上海中医药大学

出　　处：《中国健康心理学杂志》2020年第8期1135-1139,共5页China Journal of Health Psychology

基　　金：上海市嘉定区卫生和计划生育委员会卫计委科研课题(编号:2017-KY-15)。

摘　　要：目的:探索计算机认知矫正治疗对慢性精神分裂症患者社会功能的影响。方法:选取慢性精神分裂症患者100例作为研究对象,随机分为研究组和对照组各50例,对照组给予基础治疗,研究组在基础治疗上进行计算机认知矫正治疗,持续治疗24周。两组均于治疗前、治疗12周、24周及治疗后24周进行阳性和阴性症状评定量表(PANSS)、住院精神病人社会功能评定量表(SSPI)及个人和社会功能量表(PSP)评定。结果:两组患者在性别、年龄、首发年龄、病程、受教育年限、治疗前PANSS、SSPI、PSP总分方面的差异均无统计学意义(P>0.05)。组间比较:研究组PANSS总分在治疗12周、24周及治疗后24周时均低于对照组(t=-4.264,-4.331,P<0.01;t=-2.149,P<0.05);研究组SSPI总分在治疗12周、24周及治疗后24周时高于对照组(t=8.728,24.829,18.298,P<0.01);研究组PSP总分在治疗12周、24周及治疗后24周时均高于对照组(t=3.015,P<0.01;t=5.952,P<0.05;t=2.984,P<0.01)。组内比较:研究组PANSS总分在治疗24周时低于治疗12周(t=3.174,P<0.01);SSPI总分在治疗24周高于治疗12周(t=-13.749,P<0.01);PSP总分在治疗24周高于治疗12周(t=-10.803,P<0.01)。结论:计算机认知矫正治疗能够改善慢性精神分裂症患者的精神症状及其社会功能,治疗时间越长,疗效越明显,在停止治疗后仍具有一定的远期疗效。Objective:To explore the effect of Computerized Cognitive Remediation Therapy(CCRT)on social function in patients with chronic schizophrenia.Methods:A total of 100 patients with chronic schizophrenia were randomly divided into study group(n=50)and control group(n=50).The control group was given basic treatment,and the study group was treated with 24-weeks CCRT.The Positive and Negative Syndrome Scale(PANSS),Scale of Social function of Psychosis Inpatients(SSPI),Personal and Social Performance Scale(PSP)were followed up and analyzed before treatment,12 weeks,24 weeks and 24 weeks after treatment.Results:There was no significant difference between the two groups in terms of sex,age,first onset age,course of disease,years of education,total scores of PANSS,SSPI and PSP before treatment.The total score of PANSS in the study group were lower than those in the control group at 12 weeks,24 weeks and 24 weeks after treatment(t=-4.264,-4.331,-2.149;P<0.05);The total scores of SSPI in the study group were higher than those in the control group at 12 weeks,24 weeks and 24 weeks after treatment(t=8.728,24.829,18.298;P<0.01);The total scores of PSP in the study group were higher than those in the control group at 12 weeks,24 weeks and 24 weeks after treatment(t=3.015,5.952,2.984;P<0.01).In the study group,the total score of PANSS at 24 weeks of treatment was lower than that of 12 weeks after treatment(t=3.174,P<0.01);The total score of SSPI in 24 weeks of treatment was higher than that of 12 weeks of treatment(t=-13.749,P<0.01);The total score of PSP in 24 weeks of treatment was higher than that of 12 weeks of treatment(t=-10.803,P<0.01).Conclusion:CCRT can improve the mental symptoms and social function of patients with chronic schizophrenia.The longer the treatment time,the more obvious the curative effect.It still has a certain long-term effect even if the treatment is stopped.

关 键 词：计算机认知矫正治疗 慢性精神分裂症 社会功能 远期疗效 

分 类 号：R749.3[医药卫生—神经病学与精神病学]