苯并[b]荧蒽的毒性效应及对人体健康影响的研究进展  

Research progress on toxic effects of benzo [b] fluoranthene and its effects on human health

作　　者：杜宏举[1] 高珊[1] 张鹏[1] 杨庆[1] 宁钧宇[1] 李国君[1] DU Hong-ju;GAO Shan;ZHANG Peng;YANG Qing;NING Jun-yu;LI Guo-jun(Beijing Center for Disease Preven tion and Control/Beijing Research Center for Preventive Medicine,Beijing Key Laboratory of Diagnostic and Traceability Technology for Food Poisoning,Beijing 100013,China)

机构地区：[1]北京市疾病预防控制中心/北京市预防医学研究中心,食物中毒诊断溯源技术北京市重点实验室,北京100013

出　　处：《毒理学杂志》2020年第3期214-219,共6页Journal of Toxicology

基　　金：国家重点研发计划(#2018YFC1603102,#2018YFC1602703);北京市财政支持项目(空气污染与人群健康研究项目-大气细颗粒物健康效应研究及环境健康风险评估技术与应用研究)。

摘　　要：苯并[b]荧蒽(B[b]F)对人群的毒性作用及致癌风险受到日益关注,为今后B[b]F研究提供参考,本文介绍了B[b]F的动物毒性效应及人体健康影响的研究进展。B[b]F可引起实验动物致肿瘤作用、遗传和生殖发育毒性等多种毒性效应。长期暴露于含B[b]F的空气、水源等环境中的人群,致癌风险增加。今后需进一步加强B[b]F毒性作用及机制研究,以预防和控制其潜在的危害作用。In order to provide reference for the future study of benzo[b]fluoranthene(B[b]F), the research progress of its toxic effects on animals and human health were introduced. B[b]F can cause a variety of toxic effects such as tumorigenic effect, genetic and reproductive development toxicity of experimental animals. The risk of cancer increases to these people long term exposed to air and water containing B[b]F. In order to prevent and control the potential harmful effects of B[b]F, it is necessary to strengthen its toxic effect and mechanism studies in the future.

关 键 词：苯并[b]荧蒽 毒性效应 健康影响 致癌 

分 类 号：R730.2[医药卫生—肿瘤]