钯-氧化锌纳米管修饰电极同时检测多巴胺、抗坏血酸和尿酸  

Simultaneous Detection of Dopamine, Ascorbic Acid and UricAcid by Palladium-Zinc Oxide Nanotube Modified Electrode

作　　者：唐倩 陈梦妮 朱国栋 刘建允 TANG Qian;CHEN Meng-Ni;ZHU Guo-Dong;LIU Jian-Yun(College of Environmental Science and Engineering,State Environmental Protection Engineering Center for Pollution Treatment and Control in Textile Industry,Donghua University,Shanghai 201620,China;Shanghai Institute of Pollution Control and Ecological Security,Shanghai 200092,China)

机构地区：[1]东华大学环境科学与工程学院,国家环境保护纺织工业污染防治工程技术中心,上海201620 [2]上海污染控制与生态安全研究院,上海200092

出　　处：《分析化学》2020年第9期1177-1184,共8页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金项目(No.21776045)资助。

摘　　要：以PdCl 2和Zn(Ac)2为起始物,采用静电纺丝方法结合高温煅烧,成功制备了钯-氧化锌(Pd-ZnO)中空纳米管。Pd的存在改善了ZnO晶体颗粒的均匀性,调控纤维向中空管状结构转变。利用扫描电子显微镜、透射电子显微镜、X射线衍射等表征技术证明了纳米管内径为240 nm,Pd纳米粒子粒径约为80 nm,且在纳米管上均匀分布。X射线光电子能谱证明,Pd纳米粒子主要以PdO形态存在。所得的Pd-ZnO修饰玻碳电极对多巴胺(DA)、抗坏血酸(AA)和尿酸(UA)均显示出良好的催化活性。采用差分脉冲伏安法测定含DA、AA和UA的混合液,三者的氧化峰电位在此修饰电极上可完全分离,对应的线性范围分别为3.0×10^7~3.0×10^5 mol/L(R 2=0.9967)、1.0×10^5~1.0×10^3 mol/L(R 2=0.9991)和6.0×10^6~6.0×10^4 mol/L(R 2=0.9935),检出限(S/N=3)分别为1.0×10^8 mol/L、1.0×10^6 mol/L和3.0×10^6 mol/L。此电极重现性及稳定性良好,可同时测定样品中的DA、AA和UA。Palladium-zinc oxide(Pd-ZnO)hollow nanotubes were prepared by using PdCl 2 and Zn(Ac)2 as raw material through electrospinning technique combined with high temperature calcination.The presence of Pd improved the distribution of ZnO.Scanning electron microscopy,transmission electron microscopy and X-ray diffraction characterization confirmed the formation of the Pd-ZnO hollow nanofiber with an inner diameter of 240 nm.Pd nanoparticles(PdNPs)with the size of 80 nm were distributed uniformly on the nanotubes.X-ray photoelectron spectroscopy proved that PdNPs mainly existed in the form of PdO.The obtained Pd-ZnO modified glassy carbon electrode exhibited excellent catalytic activity for the oxidation of dopamine(DA),ascorbic acid(AA)and uric acid(UA).Differential pulse voltammetry was successfully applied for the simultaneous measurement of DA,AA and UA without mutual interference.The linear concentration ranges of DA,AA and UA were 3.0×10^7-3.0×10^5 mol/L(R 2=0.9967),1.0×10^5-1.0×10^3 mol/L(R 2=0.9991)and 6.0×10^6-6.0×10^4 mol/L(R 2=0.9935),with the corresponding detection limits(S/N=3)of 1.0×10^8 mol/L,1.0×10^6 mol/L and 3.0×10^6 mol/L,respectively.The Pd-ZnO electrode with good reproducibility and stability was applicable for the simultaneous measurement of DA,AA and UA.

关 键 词：多巴胺 抗坏血酸 尿酸 钯 氧化锌 脉冲伏安法 

分 类 号：R446.1[医药卫生—诊断学] O657.1[医药卫生—临床医学]