肺腺癌和肺鳞癌的能谱CT参数特征分析  

ANALYSIS OF PARAMETERS OF ENERGY SPECTRUM CT IN ADENOCARCINOMA AND SQUAMOUS CELL CARCINOMA OF LUNG

作　　者：王洪峰[1] Wang Hongfeng(CT Unit,Tangshan People’s Hospital,Tangshan 063000,China)

机构地区：[1]河北省唐山市人民医院CT室,063000

出　　处：《中国煤炭工业医学杂志》2020年第3期298-302,共5页Chinese Journal of Coal Industry Medicine

基　　金：河北省卫生厅科研基金项目(编号:20171299)。

摘　　要：目的探讨能谱CT鉴别诊断肺鳞癌与肺腺癌的应用价值。方法选择2018年12月—2019年12月于我院行能谱CT检查且经病理证实的95例肺癌患者(鳞癌52例,腺癌43例)为研究对象,比较二组患者平扫及增强扫描后动脉期40 keV、100 keV能量水平CT值、40~100 keV能谱曲线斜率、碘浓度的不同,分析肺鳞癌与肺腺癌的能谱参数特征。结果平扫鳞癌组40 keV、100 keV单能量CT值均高于腺癌组,40keV单能量CT值高于腺癌组,差异有统计学意义(P<0.05);100keV单能量CT值与腺癌组比较,差异无统计学意义(P>0.05)。鳞癌组40~100keV能谱曲线斜率及碘浓度均高于腺癌组,差异均有统计学意义(均P<0.05)。增强扫描腺癌组动脉期40keV、100keV单能量CT值均高于鳞癌组,差异均有统计学意义(均P<0.05);腺癌组40~100keV能谱曲线斜率及碘浓度均显著高于鳞癌组,差异均有统计学意义(均P<0.05)。ROC曲线分析显示动脉期碘浓度对鉴别肺鳞癌与肺腺癌有较高的灵敏度(79.0%)与特异度(86.2%)。结论能谱扫描能够借助单能量CT值、40~100keV能谱曲线斜率、碘浓度等参数反映肺鳞癌和腺癌的差异,为肺鳞癌和腺癌的鉴别诊断提供影像学依据。Objective To explore the value of energy spectrum CT in differential diagnosis of squamous cell carcinoma and adenocarcinoma of lung.Methods From December 2018 to December 2019,ninety-five lung cancer patients(52 cases of squamous cell carcinoma and 43 cases of adenocarcinoma)examined by EDCT and confirmed by pathology in Tangshan People’s Hospital were selected as the study objects.The differences of 40 keV and 100 keV energy level CT value,40-100 keV energy curve skew rate and iodine concentration in arterial phase between the two groups were compared,and the characteristics of EDX parameters of lung squamous cell carcinoma and lung adenocarcinoma were analyzed.Results The single energy CT value of 40 keV and 100 keV in plain scan squamous cell carcinoma group was higher than that of adenocarcinoma group,and the single energy CT value of 40 keV was higher than that of adenocarcinoma group,the difference was statistically significant(P<0.05);there was no significant difference in 100 keV between the two groups(P>0.05).The slope and iodine concentration of 40-100 keV energy spectrum curve in squamous cell carcinoma group were higher than those in adenocarcinoma group(P<0.05).The single energy CT value of 40 keV and 100 keV in the arterial phase of the adenocarcinoma group was significantly higher than that of the squamous cell carcinoma group(P<0.05);the slope and iodine concentration of 40-100 keV energy spectrum curve in the adenocarcinoma group were significantly higher than those in the squamous cell carcinoma group(P<0.05).ROC curve analysis showed that iodine concentration in arterial phase was sensitive in differential diagnosis of squamous cell carcinoma and adenocarcinoma of the lung with sensitivity(79.0%)and specificity(86.2%).Conclusion With the help of single energy CT value,40-100 keV curve slope,iodine concentration and other parameters,energy spectrum scan can reflect the difference between squamous cell carcinoma and adenocarcinoma of the lung,and provide imaging basis for the differential diag

关 键 词：肺鳞癌 肺腺癌 X线计算机 能谱扫描 

分 类 号：R734.2[医药卫生—肿瘤]