磁共振全身弥散加权成像与CT对淋巴瘤化疗疗效评价的比较研究  

Comparative Study of Whole Body Diffusion Weighted Imaging and CT in Evaluating the Efficacy of Chemotherapy for Lymphoma

作　　者：刘永欣 李琳琳[1] 马静 LIU Yongxin;LI Linlin;MA Jing(Emergency Department,The First Affiliated Hospital of Hebei North University,Zhangjiakou 075000,Hebei,P.R.China)

机构地区：[1]河北北方学院附属第一医院急诊科,河北张家口075000

出　　处：《影像科学与光化学》2020年第5期929-933,共5页Imaging Science and Photochemistry

摘　　要：本研究旨在比较磁共振全身弥散加权成像(WB-DWI)与计算机断层扫描(CT)对淋巴瘤化疗疗效评价作用的差异。选取60例淋巴瘤患者作为病例组,另择同期健康志愿者43例作为对照组。结果显示,在WB-DWI与CT检查中病灶淋巴结呈明显高信号,经1、4、8个周期化疗后,WBDWI与CT的信号强度较化疗前均明显降低,WB-DWI对淋巴瘤病灶大小、病灶范围及病灶数目显示符合率均明显高于CT检查(P<0.05)。病例组各检查部位ADC值及平均ADC值均低于对照组(P<0.05)。病例组治疗前后ADC值、化疗前、化疗期间与化疗后ADC值比较差异有统计学意义(P<0.05)。总体上,WB-DWI对淋巴瘤化疗疗效评价的能力优于CT。The purpose of this study was to compare the effect of whole body diffusion weighted imaging(WB-DWI)with that of computed tomography(CT)in evaluating the efficacy of chemotherapy for lymphoma.60patients with lymphoma were selected as the case group and 43healthy volunteers were selected as the control group.The results showed that the lymph nodes in the lesion showed significantly high signal in WB-DWI and CT examination.After 1,4and 8cycles of chemotherapy,the signal intensity on the images of WB-DWI and CT was significantly lower than that before chemotherapy,and the coincidence rate of WB-DWI in the lesion size,lesion range and number of lesions were significantly higher than that of CT examination(P<0.05).ADC values and the average ADC values of each site in the case group were lower than those of the control group(P<0.05).There were statistically significant differences in ADC values before and after treatment,before and during chemotherapy,and after chemotherapy in the case group(P<0.05).In general,WB-DWI is better than CT in evaluating the efficacy of chemotherapy in lymphoma,which is worthy of clinical application.

关 键 词：磁共振全身弥散加权成像 计算机断层扫描 淋巴瘤 化疗 疗效评价 

分 类 号：R733.1[医药卫生—肿瘤]