拉克替醇散在肠镜检查准备中的应用效果  

Effects of lactitol powder in the intestinal preparation for enteroscopy examination

作　　者：赵涛 曲峰 张信 ZHAO Tao;QU Feng;ZHANG Xin(Department of Digestive Medicine,Xinyang Hospital District,No.990 Hospital of Henan Xinyang Joint Service and Security Force,Henan Xinyang 464000,China)

机构地区：[1]河南信阳联勤保障部队第990医院信阳院区消化内科,河南信阳464000

出　　处：《临床药物治疗杂志》2020年第8期39-43,共5页Clinical Medication Journal

摘　　要：目的探讨拉克替醇散与复方聚乙二醇电解质散在肠镜检查肠道准备中的应用效果。方法选取2018年1-12月在我院行结肠镜检查者210例,根据使用的药物分为观察组118例和对照组92例。观察组给予拉克替醇散,对照组给予复方聚乙二醇电解质散,观察2组患者的肠道清洁、肠道气泡等情况。结果观察组左半结肠、横结肠、右半结肠波士顿肠道准备量表(BBPS)评分以及BBPS总评分分别为(2.97±0.36)分、(2.80±0.45)分、(2.30±0.52)分和(8.11±0.92)分,明显高于对照组(P<0.05);观察组肠道内气泡产生情况优于对照组(P<0.05);观察组服药到初次排便时间、服药到排便结束时间分别为(60.13±21.18)min和(187.79±34.49)min,明显比对照组短(P<0.05);观察组和对照组肠道准备前后血钠、血钾、血钙和血磷水平比较差异无统计学意义(P>0.05);观察组恶心呕吐、腹胀比例分别为6.78%和4.24%,明显低于对照组(P<0.05)。结论与复方聚乙二醇电解质散比较,拉克替醇散在肠镜检查肠道准备中的效果较好,不良反应少,值得临床推广使用。Objective To explore the application effect of lactol powder and compound polyethylene glycol electrolyte powder in intestinal preparation for enteroscopy.Methods 210 patients who underwent colonoscopy in our hospital from January 2018 to December 2018 were selected and divided into observation group(n=118)and control group(n=92)according to the selected drugs,the observation group was given lactitol powder,while the control group was given compound polyethylene glycol electrolyte powder.The intestinal cleanliness,intestinal bubbles of the two groups,etc.were compared.Results The Boston gut preparation scale(BBPS)scores of left,transverse and right colons and the total BBPS scores of the observation group were(2.97±0.36),(2.80±0.45),(2.30±0.52)and(8.11±0.92),respectively,which were significantly higher than those of the control group(P<0.05).The amount of intestinal bubbles in the observation group was less than that in the control group(P<0.05).The time from taking medicine to the first defecation and to the end of defecation in the observation group were(60.13±21.18)min and(187.79±34.49)min,which were significantly shorter than those in the control group(P<0.05).There were no significant differences in serum sodium,potassium,calcium and phosphorus levels between the observation group and the control group before and after intestinal preparation(P>0.05).The proportion of nausea,vomiting and abdominal distension in the observation group were 6.78%and 4.24%,which was significantly lower than that in the control group(P<0.05).Conclusion Compared with the compound polyethylene glycol electrolyte powder,lactitol powder has better effect and less adverse drug events in intestinal preparation for enteroscopy,and is worthy of clinical application.

关 键 词：拉克替醇散 复方聚乙二醇电解质散 肠镜 肠道准备 

分 类 号：R574[医药卫生—消化系统]