TASK-3:New Target for Pain-Relief  

作　　者：Wen-Jing Ren Henning Ulrich Alexey Semyanov Peter Illes Yong Tang 

机构地区：[1]International Collaborative Centre on Big Science Plan for Purine Signaling,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China [2]Acupuncture and Chronobiology Key Laboratory of Sichuan Province,Chengdu 610075,China [3]Department of Biochemistry,Institute of Chemistry,University of Sao Paulo,Sao Paulo 05508,Brazil [4]Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry,Russian Academy of Sciences,Moscow,Russia 117997 [5]Rudolf-Boehm-Institut fiir Pharmakologie und Toxikologie,Universitaet Leipzig,04109 Leipzig,Sachsen,Germany

出　　处：《Neuroscience Bulletin》2020年第8期951-954,共4页神经科学通报（英文版）

基　　金：supported by the National Key R&D Program of China (2019YFC1709101);The Project First-Class Disciplines Development of Chengdu University of TCM (CZYHW1901);Sao Paulo Research Foundation (FAPESP 2018/07366-4);the National Natural Science Foundation of China (81904312 and 81774437);the Sichuan Science and Technology Program,China (2019YFH0108,2018HH0123,and 2018SZ0257)。

摘　　要：Morphine and other opioids are among the most effective analgesics for treating pain.However,drug dependence and other deleterious side effects of opioids have limited their clinical applicability.Recent studies suggest that the use of opioids for pain control may even exacerbate disease outcomes in some pain-producing conditions,such as acute pancreatitis[1].

关 键 词：RELIEF DELETE producing 

分 类 号：R971[医药卫生—药品]