Supported by Capital’s Funds for Health Improvement and Research(No.2024-2-4087);Central Guidance for Local Scientific and Technological Development Funding Projects(No.2022ZY0026).
Dear Editor,X-linked retinoschisis(XLRS)is a rare X-linked recessive disorder predominantly afflicting young males.The schisis of the retinal layers is a result of deleterious mutations in the RS1 gene.Insufficient ep...
NIH grant GM132713(K.W.);CHOP Research Institute and the Fundamental Research Funds for the Central Universities,Sun Yat-sen University(No.23ptpy119,to L.F).
Various machine-learning models,including deep neural network models,have already been developed to predict deleteriousness of missense(non-synonymous)mutations.Potential improvements to the current state of the art,h...
funding support provided by the National Institute of Aging through grant 1K99AG065200-01A1 to RHS。
The ability to protect cellular components in the face of deleterious conditions, such as exposure to chemical poisons, damaging radiation, or excessive heat, is crucial to organismal viability.
funded the Spanish Ministerio de Economiay Competitividad (Programa Ramón y Cajal: RYC2017-21804)
Microglial cells,the“macrophages”from the central nervous system(CNS),perform a variety of roles necessary to keep the homeostasis in the healthy brain.However,microglial cells are best known for their role as“firs...
supported by the National Key R&D Program of China (2019YFC1709101);The Project First-Class Disciplines Development of Chengdu University of TCM (CZYHW1901);Sao Paulo Research Foundation (FAPESP 2018/07366-4);the National Natural Science Foundation of China (81904312 and 81774437);the Sichuan Science and Technology Program,China (2019YFH0108,2018HH0123,and 2018SZ0257)。
Morphine and other opioids are among the most effective analgesics for treating pain.However,drug dependence and other deleterious side effects of opioids have limited their clinical applicability.Recent studies sugge...
supported by the National Natural Science Foundation of China(11772014,51475012,11272021);the Importation and Development of High-Caliber Talents Project of Beijing Municipal Institutions(CIT&TCD201304048)
In the study,an improved time difference mapping(I-TDM) method is proposed to locate the acoustic emission(AE) source in a composite plate.The acoustic velocity in a composite plate with fiber fractures and matrix cra...
Project supported by the National.Natural Science Foundation of China (No. 71571189)
The component-based business architecture integration of military information systems is a popu- lar research topic in the field of military operational research. Identifying enterprise-level business components is an...