八宝丹胶囊治疗原发性肝癌化疗栓塞术后综合征临床研究  

Clinical Study on Babaodan Capsules for Postoperative Syndrome in Patients Undergoing Chemoembolization for Primary Hepatocellular Carcinoma

作　　者：徐意 李伟 楼妙姿 徐超 XU Yi;LI Wei;LOU Miaozi;XU Chao

机构地区：[1]金华广福医院消化科,浙江金华321000

出　　处：《新中医》2020年第16期104-106,共3页New Chinese Medicine

摘　　要：目的:观察八宝丹胶囊对原发性肝癌患者化疗栓塞术后综合征的临床疗效。方法:选择原发性肝癌患者83例,按随机数字表法分为对照组41例和观察组42例。对照组采用动脉化疗栓塞术治疗,观察组在对照组基础上口服八宝丹胶囊。比较2组临床疗效和症状持续时间,评价治疗前后肝功能和Karnofsky评分变化。结果:观察组总有效率为73.81%,高于对照组46.34%,差异有统计学意义(P<0.05)。观察组发热、肝区疼痛、恶心呕吐和腹胀持续时间短于对照组,差异均有统计学意义(P<0.05)。治疗前,2组谷草转氨酶(AST)、总胆红素(TBil)及谷丙转氨酶(ALT)水平比较,差异无统计学意义(P>0.05)。治疗后,观察组AST、TBil及ALT水平较治疗前降低,且低于对照组,差异均有统计学意义(P<0.05)。治疗前,2组Karnofsky评分比较,差异无统计学意义(P>0.05)。治疗后,对照组Karnofsky评分较治疗前降低,观察组Karnofsky评分较治疗前升高,且观察组Karnofsky评分高于对照组,差异均有统计学意义(P<0.05)。结论:八宝丹胶囊对肝癌化疗栓塞术后综合征患者临床疗效良好,且可改善患者肝功能。objective:To observe the clinical effect of Babaodan capsules for postoperative syndrome in patients who had undergone chemoembolization for primary hepatocellular carcinoma.Methods:A total of 83 patients with primary hepatocellular carcinoma were divided into the control group(41 cases)and the observation group(42 cases)according to the random number table method.The control group was treated by transarterial radioembolization,and the observation group was additionally treated with oral administration of Babaodan capsules based on the treatment of the control group.The clinical effect and symptom duration in the two groups were compared,and the changes of liver function and Karnofsky score before and after treatment were evaluated.Results:The total effective rate was 73.81% in the observation group,higher than that of 46.34% in the control group,the difference being significant(P<0.05).The duration of fever,liver-area pain,nausea and vomiting as well as abdominal distension in the observation group was shorter than that in the control group respectively,differences being significant(P<0.05).Before treatment,there was no significant difference in the comparison of the levels of aspartate transaminase(AST),total bilirubin(TBil)and alanine transaminase(ALT)between the two groups(P>0.05).After treatment,the levels of AST,TBil and ALT in the observation group were decreased when compared with those before treatment and lower than those in the control group,differences being significant(P<0.05).Before treatment,there was no significant difference in the comparison of the Karnofsky score between the two groups(P>0.05).After treatment,the Karnofsky score in the control group was decreased when compared with that before treatment,while the Karnofsky score in the observation group was increased;the Karnofsky score in the observation group was higher than that in the control group,differences being significant(P<0.05).Conclusion:Babaodan capsules have significant clinical effect in treating patients with postoperative synd

关 键 词：原发性肝癌 化疗栓塞术后综合征 八宝丹胶囊 肝功能 KARNOFSKY评分 

分 类 号：R735.7[医药卫生—肿瘤]