T-2毒素的危害及脱毒研究进展  

Research Progress on the Toxicity and Detoxification of T-2 Toxin

作　　者：宋佳 范寰[2] 闫雪 王文杰[2] 赵晨 SONG Jia;FAN Huan;YAN Xue;WANG Wen-jie;ZHAO Chen(Academy of National Food and Strategic Reserves Administration,Beijing 100037,China;Tianjin Animal Science and Veterinary Research Institute,Tianjin 300381,China;New Hope Liuhe Co.,Ltd./Key Laboratory of Feed and Livestock and Poultry Products Quality&Safety Control,Ministry of Agriculture,Chengdu,Sichuan 610023,China)

机构地区：[1]国家粮食和物资储备局科学研究院,北京100037 [2]天津市畜牧兽医研究所,天津300381 [3]新希望六和股份有限公司/农业农村部饲料及畜禽产品质量安全控制重点实验室,四川成都610023

出　　处：《粮油食品科技》2020年第5期194-199,共6页Science and Technology of Cereals,Oils and Foods

基　　金：“十三五”国家重点研发计划课题(2016Y FD0501207);天津市农委“天津市奶牛现代农业产业技术体系创新团队专项资金”(ITTCRS2018022)。

摘　　要：T-2毒素是由镰刀属菌产生的一种次级代谢产物,属于单端孢霉烯族常见的A型真菌毒素。T-2毒素具有强毒性,它不仅会污染田间作物和库存谷物造成粮食产后损失,还会对人畜的健康造成巨大损害,是近年来全球范围内粮食行业和畜牧业防治的重点。目前关于T-2毒素生物毒性的研究比较深入,但关于T-2毒素脱毒,尤其是生物脱毒的研究较少。综述了T-2毒素的危害致毒机理及物理、化学、生物等脱毒方法。将获取高效脱毒酶和开发脱毒工艺作为研究重点,利于我国粮食、畜牧、副产物深加工等行业的良性发展。T-2 toxin is a secondary metabolite produced by Fusarium spp.,and belongs to the type A mycotoxins in the cephalosporins family.T-2 toxin is highly toxic,and it pollutes not only crops in the field,but also granary which leads the post-harvest lost of grain,furthermore,it causes huge damage to human and animal health.Therefore,it becomes world widely the target to be prevented and controlled in the food industry and livestock industry in recent years.At present,the research on the biological toxicity of T-2 toxin is more indepth,but it still lacks adequate study on detoxification of T-2 toxin,especially the biological detoxification.The harm,mechanism and physical,chemical and biological methods of detoxification of T-2 toxins were reviewed.Focusing on the acquisition of efficient detoxification enzymes and the development of detoxification processes are conducive to the healthy development of multiple industries in China,such as grain industry,livestock industry,and by-product deep processing.

关 键 词：T-2毒素 致毒机理 代谢产物 生物脱毒 

分 类 号：TS213.2[轻工技术与工程—粮食、油脂及植物蛋白工程]